Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University, 582 Bunkyodai-Midorimachi, Ebetsu, Hokkaido 069-8501, Japan.
Department of Veterinary Ophthalmology, Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoinooka, Imabari, Ehime, 794-8555, Japan.
J Vet Med Sci. 2020 Jul 10;82(7):922-925. doi: 10.1292/jvms.20-0169. Epub 2020 May 21.
The purpose of this study was to investigate the effects of pupil diameter on canine visual evoked potentials with pattern stimulation (P-VEP). Atropine eye drop (1.0%) was applied to both eyes as a cycloplegic drug, and tafluprost eye drop (0.015%) was applied to one eye that was selected randomly for miosis (miosis group). The other eye did not receive tafluprost (mydriasis group). P-VEP was recorded at three pattern sizes. The P100 implicit time at a small pattern size in the mydriasis group was significantly prolonged compared to the miosis group. We hypothesized that the prolonged P100 implicit time under mydriatic conditions was due to increased spherical aberrations and concluded that mydriatic conditions affected P100 implicit time in canine P-VEP recordings.
本研究旨在探讨瞳孔直径对犬图形视觉诱发电位（P-VEP）的影响。采用 1.0%阿托品滴眼剂作为睫状肌麻痹剂，对双眼进行散瞳，同时随机选择一只眼滴用他氟前列素滴眼剂（0.015%）缩瞳（缩瞳组），另一只眼不滴用他氟前列素（散瞳组）。在三种图形大小下记录 P-VEP。与缩瞳组相比，散瞳组在小图形尺寸下 P100 潜伏期明显延长。我们假设在散瞳状态下 P100 潜伏期延长是由于球差增加所致，并得出结论，散瞳状态影响犬 P-VEP 记录中的 P100 潜伏期。
