Kagawa Takanori, Imamura Tomohiko, Enseki Mayumi, Tabata Hideyuki, Furuya Hiroyuki, Niimura Fumio, Mochizuki Hiroyuki
Department of Pediatrics, Tokai University School of Medicine.
Department of Preventive Medicine, Tokai University School of Medicine.
Arerugi. 2020;69(3):184-191. doi: 10.15036/arerugi.69.184.
In order to determine the optimal breathing method for childhood lung sound analyses, it is important to study the effect of airflow on the parameters of lung sounds.
Sixty-one well-controlled children with atopic asthma (median; 12 years) participated. After confirming that there was no wheezing or respiratory symptoms, the lung sound spectrums of the inspiratory flow before and after inhalation of a β stimulant were analyzed. At the same time, their lung function was measured by a spirogram and the forced oscillation technique.
Before β agonist inhalation, the area under the entire curve (A) and 99% frequency (F) in the lung sound of inspiratory flow around 2.0L/s due to slightly strong breathing were significantly higher than the lung sound of inspiratory flow around 1.0L/s due to rest breathing. However, no marked differences were observed in the lung sound parameters based on the lung sound spectrum. The improvement in the lung sound parameters after β agonist inhalation was clearer at an inspiratory flow around 1.0L/s than that around 2.0L/s.
The present study showed that changes after β agonist inhalation and the correlation with the lung function parameters were clear during resting breathing. This method may be used for the long-term montoring of children with asthma.
为了确定儿童肺音分析的最佳呼吸方法，研究气流对肺音参数的影响很重要。
61名病情得到良好控制的特应性哮喘儿童（中位数为12岁）参与了研究。在确认没有喘息或呼吸道症状后，分析吸入β激动剂前后吸气气流的肺音频谱。同时，通过肺量计和强迫振荡技术测量他们的肺功能。
在吸入β激动剂之前，由于稍用力呼吸导致吸气气流在2.0L/s左右时肺音的全曲线下面积（A）和99%频率（F）显著高于休息呼吸时吸气气流在1.0L/s左右时的肺音。然而，基于肺音频谱的肺音参数未观察到明显差异。吸入β激动剂后，在吸气气流1.0L/s左右时肺音参数的改善比在2.0L/s左右时更明显。
本研究表明，在静息呼吸期间，吸入β激动剂后的变化以及与肺功能参数的相关性很明显。该方法可用于哮喘儿童的长期监测。
