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儿童患者应用杂交插管行长期 CentriMag 双心室辅助以桥接移植。

Long term CentriMag biventricular support using hybrid cannulation as a bridge to transplant in a pediatric patient.

机构信息

Department of Cardiothoracic Surgery, Queen Mary Hospital, Room 308, New Clinical Building, Pokfulam Road, Hong Kong, Hong Kong.

Division of Paediatric Cardiology, Queen Mary Hospital, Room 321D, New Clinical Building, Pokfulam Road, Hong Kong, Hong Kong.

出版信息

J Artif Organs. 2020 Dec;23(4):374-377. doi: 10.1007/s10047-020-01177-w. Epub 2020 May 20.

Abstract

Paracorporeal continuous-flow ventricular assist devices designed for short-term support can also potentially provide long-term circulatory support as bridges to transplantation in children. We describe the long-term use of the CentriMag biventricular assist device with multiple pump changes in a 9-year-old boy with idiopathic-dilated cardiomyopathy. The initially implanted Berlin Heart EXCOR pumps were replaced by CentriMag due to thromboembolic complications. The CentriMag pumps were exchanged 15 times due to clot and fibrin formation or when the pumps reached their expiration dates. Connecting CentriMag to Berlin Heart EXCOR cannulae effectively served as an alternative long-term hybrid bridge to transplantation for 235 days. The patient successfully underwent a transplant after 284 days. Judicious pump monitoring and timely pump exchanges can potentially overcome device-related complications and extend the duration on support.

摘要

体外连续流心室辅助装置设计用于短期支持,也有可能作为桥接物,为儿童提供长期循环支持,以进行移植。我们描述了一种 9 岁男孩使用 CentriMag 双心室辅助装置的长期应用情况,该男孩患有特发性扩张型心肌病,经历了多次泵更换。最初植入的柏林心脏 EXCOR 泵因血栓栓塞并发症而被 CentriMag 取代。由于血栓和纤维蛋白形成,或者当泵达到使用期限时,CentriMag 泵已经更换了 15 次。将 CentriMag 与柏林心脏 EXCOR 插管连接,有效地作为替代的长期杂交桥接物,为移植提供了 235 天的支持。患者在 284 天后成功进行了移植。明智的泵监测和及时的泵更换可以潜在地克服与设备相关的并发症,并延长支持时间。

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