Bowling Green State University, Bowling Green, Ohio, USA.
Int J Eat Disord. 2020 Jul;53(7):1021-1033. doi: 10.1002/eat.23287. Epub 2020 May 21.
Research has demonstrated mixed results regarding the direction of the association between vagal activation and disordered eating. The current meta-analysis examined studies testing the link between resting-state heart rate variability indices of vagal activation (vmHRV), and both clinical and subthreshold disordered eating.
A systematic search of the literature resulted in the inclusion of studies that were correlational (associations between HRV and disordered eating symptoms) and that examined group differences (e.g., control group vs. disordered eating group), for a total of 36 samples.
Findings indicated a small but reliable association of vmHRV with disordered eating, r = 0.12, indicating greater vagal activation in individuals with disordered eating compared to those with little or no disordered eating behavior. Moderation analyses identified predictors of the vmHRV/disordered eating association. Bulimia nervosa was found to have a large, positive effect size with vmHRV, r = 0.60, which was significantly greater than all other types of disordered eating, Q = 10.74, p = .047. Compared to subthreshold disordered eating, clinical eating disorders demonstrated significant, persistent increased vagal activation with a medium, reliable effect size, r = 25, Q = 3.94, p = .045.
These insights contribute to an improved understanding of the pathophysiology in disordered eating.
研究表明，迷走神经激活与饮食失调之间的关联方向存在混合结果。本荟萃分析研究了静息状态下迷走神经激活的心率变异性指数（vmHRV）与临床和亚临床饮食失调之间的关系。
系统检索文献，纳入了相关性研究（HRV 与饮食失调症状之间的关联）和组间差异研究（例如，对照组与饮食失调组），共 36 个样本。
研究结果表明，vmHRV 与饮食失调之间存在微弱但可靠的关联，r = 0.12，表明饮食失调个体的迷走神经激活程度高于饮食失调行为较少或没有的个体。调节分析确定了 vmHRV/饮食失调关联的预测因素。神经性贪食症与 vmHRV 的正相关效应量较大，r = 0.60，明显大于其他类型的饮食失调，Q = 10.74，p =.047。与亚临床饮食失调相比，临床饮食障碍表现出显著且持续增加的迷走神经激活，中等可靠的效应量，r = 25，Q = 3.94，p =.045。
这些发现有助于更好地理解饮食失调的病理生理学。
