Department of Pediatric Cardiac Surgery, National Heart Institute, Kuala Lumpur, Malaysia.
Department of Pediatric Cardiology, National Heart Institute, Kuala Lumpur, Malaysia.
Interact Cardiovasc Thorac Surg. 2020 Aug 1;31(2):221-227. doi: 10.1093/icvts/ivaa069.
This study aims to review our institutional experience of ductal stenting (DS) on the growth of pulmonary arteries (PAs) and surgical outcomes of PA reconstruction in this subset of patients.
This is a retrospective study done in neonates and infants up to 3 months of age with duct-dependent pulmonary circulation who underwent DS from January 2014 to December 2015. Post-stenting PA growth, surgical outcomes of PA reconstruction, post-surgical re-interventions, morbidity and mortality were analysed.
During the study period, 46 patients underwent successful DS, of whom 38 underwent presurgery catheterization and definite surgery. There was significant growth of PAs in these patients. Biventricular repair was done in 31 patients while 7 had univentricular palliation. Left PA augmentation was required in 13 patients, and 10 required central PA augmentation during surgery. The mean follow-up period post-surgery was 4.5 ± 1.5 years. No significant postoperative complications were seen. No early or follow-up post-surgery mortality was seen. Four patients required re-interventions in the form of left PA stenting based on the echocardiography or computed tomography evidence of significant stenosis.
DS provides good short-term palliation and the growth of PAs. However, a significant number of stented patients require reparative procedure on PAs at the time of surgical intervention. Acquired changes in the PAs following DS may be the reason for reintervention following PA reconstruction.
本研究旨在回顾我们在有导管依赖性肺循环的新生儿和 3 个月以下婴儿中进行的导管内支架置入术(DS)的经验,以及这些患者肺动脉(PA)重建的手术结果。
这是一项回顾性研究,纳入了 2014 年 1 月至 2015 年 12 月期间接受 DS 的伴有导管依赖性肺循环的新生儿和 3 个月以下婴儿。分析了支架置入后 PA 生长情况、PA 重建的手术结果、术后再干预、发病率和死亡率。
研究期间,46 例患者成功进行了 DS,其中 38 例患者进行了术前导管检查和明确的手术。这些患者的 PA 明显生长。31 例患者行双心室修复术,7 例患者行单心室姑息手术。13 例患者需要左 PA 增粗,10 例患者在手术中需要中央 PA 增粗。术后平均随访时间为 4.5±1.5 年。未观察到明显的术后并发症。无早期或随访期间术后死亡。4 例患者根据超声心动图或 CT 证据显示明显狭窄,需要进行左 PA 支架置入的再干预。
DS 可提供良好的短期姑息治疗和 PA 生长。然而,相当数量的支架置入患者在手术干预时需要对 PA 进行修复性手术。DS 后 PA 获得性改变可能是 PA 重建后再次干预的原因。