Sabbatani S, Monti M, Fini A
Infectious Diseases Department, Maggiore-C.A. Pizzardi Hospital, Bologna, Italy.
Int J Biol Markers. 1988 Apr-Jun;3(2):127-8. doi: 10.1177/172460088800300209.
A total of 104 patients with various liver diseases were studied. Hepatic biopsy was performed and the AST, ALT and TPA in serum were measured. Higher levels of TPA, AST and ALT were found in CAH and LC, lower in CPH and MHP. High serum TPA values, usually suggesting the possibility of neoplasm, should be considered with attention. A follow-up with periodic TPA assays (in addition to AST and ALT) is suggested in patients with acute hepatitis, in order to predict further possible complications such as CAH and LC.
共对104例患有各种肝脏疾病的患者进行了研究。进行了肝活检，并检测了血清中的谷草转氨酶（AST）、谷丙转氨酶（ALT）和组织多肽抗原（TPA）。发现慢性活动性肝炎（CAH）和肝硬化（LC）患者的TPA、AST和ALT水平较高，慢性迁延性肝炎（CPH）和轻度肝炎（MHP）患者的水平较低。血清TPA值升高通常提示有肿瘤的可能性，应予以关注。建议对急性肝炎患者进行定期TPA检测（除AST和ALT外）随访，以预测进一步可能出现的并发症，如CAH和LC。
