Emerg Infect Dis. 2020 Jun;26(6):1291-1294. doi: 10.3201/eid2606.190233.
The annual incidence rate of community-associated Clostridioides difficile infections in Quebec, Canada, has increased by 33.3%, from 0.51 (2008) to 0.68 (2015) cases/100,000 population, while incidence of healthcare-associated cases remained relatively stable. Possible causes include increased disease severity, increased antimicrobial drug use, emergence of virulent strains, and heightened physician awareness.
在加拿大魁北克,社区获得性艰难梭菌感染的年发病率增加了 33.3%,从 0.51(2008 年)增至 0.68(2015 年)例/10 万人,而医疗保健相关性感染的发病率仍相对稳定。可能的原因包括疾病严重程度增加、抗菌药物使用增加、毒力菌株的出现以及医生认识的提高。