The Ohio State University College of Medicine, Columbus, OH 43221, USA.
Appl Physiol Nutr Metab. 2020 Oct;45(10):1066-1070. doi: 10.1139/apnm-2020-0073. Epub 2020 May 22.
Beginning with conception and continuing through childhood and adolescence, the word "strength" connotes the totality of optimal early bone and tissue growth; neural wiring of the brain; and acquisition of fine motor, gross motor, language, and socioemotional skills. The robustness of each of these attributes depend on 3 critical epigenetic (external) factors: the quality of nutrition; positive adult nurturing; and experiences acquired within a stimulating, safe environment that affords free exploration. This review highlights the relationship between the epigenetic factors in the period of conception to age 2 years and a child's future health, cognitive capacity, and social aptitude, which collectively comprise their "strength". This paper was presented as part of the 2018 Strength Summit conference entitled, . Strength in infants signifies the totality of optimal early growth and neural wiring of the brain. Strength at this life stage also includes the acquisition of motor, language, and socioemotional skills. Three epigenetic factors are critical during birth to 24 months: nutrition, nurturing, and free exploration.
从受孕开始，一直持续到儿童期和青春期，“力量”一词表示的是早期骨骼和组织的最佳生长、大脑的神经连接以及精细运动、大运动、语言和社会情感技能的获得的总和。这些属性的稳健性取决于 3 个关键的表观遗传（外部）因素：营养质量、积极的成人养育以及在刺激、安全的环境中获得的自由探索经验。这篇综述强调了受孕到 2 岁期间的表观遗传因素与儿童未来健康、认知能力和社交能力之间的关系，这些因素共同构成了他们的“力量”。本文是作为 2018 年“力量峰会”会议的一部分提出的，会议主题为“婴儿的力量：大脑发育和未来健康的基础”。婴儿的力量代表了早期最佳生长和大脑神经连接的总和。在这个生命阶段，力量还包括运动、语言和社会情感技能的获得。在出生到 24 个月期间，有 3 个表观遗传因素至关重要：营养、养育和自由探索。
