Wang Xiaoyu, Zhang Manfei, Han Jianhui, Wang Hao, Li Song
Department of Stomatology, Beijing Tian Tan Hospital, Capital Medical University, No.119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, PR China; Department of Orthodontics, Beijing Stomatological Hospital, Capital Medical University, No.4 Tiantan Xili, Dongcheng District, Beijing, 100050, PR China.
Department of Orthodontics, Beijing Stomatological Hospital, Capital Medical University, No.4 Tiantan Xili, Dongcheng District, Beijing, 100050, PR China.
Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110085. doi: 10.1016/j.ijporl.2020.110085. Epub 2020 May 5.
Maxillary sinus disease is frequently observed in patients with unilateral cleft lip and palate (UCLP). The anatomical variations of maxillary sinus and maxilla may play a role in the high incidence of sinusitis. The aims of this study were to evaluate and compare the three-dimensional (3D) structural features of maxillary sinus and maxilla in UCLP adolescent patients between the defect and non-defect sides, and investigate the morphological relationship between the maxillary sinus and maxilla on the defect side by using cone-beam computed tomography (CBCT).
CBCT images were acquired from 42 UCLP adolescent patients. Maxillary sinus and maxilla on the defect and non-defect sides were segmented respectively and assessed three dimensionally, and the comparison was performed by paired t-test. A multiple linear regression was conducted to investigate the morphological relationship between the maxillary sinus and maxilla on the defect side.
No statistically significant difference was observed in any parameter of the maxillary sinus between the defect and non-defect sides (P > 0.05). Significant differences were observed in the length, anterior width, anterior height, and volume of the maxilla between the defect side and non-defect sides (P < 0.05). The parameters of maxillary sinus were significant related to the posterior width and height of maxilla on the defect side.
Adolescent patients with UCLP present similar 3D structural features of the maxillary sinus on both sides. Significant differences of the maxilla between the defect and non-defect sides were displayed in the area adjacent to the defect but not showed in the posterior portion of maxilla. Certain structures of the posterior portion of maxilla contribute to the variability of maxillary sinus.
单侧唇腭裂（UCLP）患者中上颌窦疾病较为常见。上颌窦和上颌骨的解剖变异可能是鼻窦炎高发的原因之一。本研究旨在评估和比较UCLP青少年患者缺损侧和非缺损侧上颌窦及上颌骨的三维（3D）结构特征，并通过锥形束计算机断层扫描（CBCT）研究缺损侧上颌窦与上颌骨的形态关系。
收集42例UCLP青少年患者的CBCT图像。分别对缺损侧和非缺损侧的上颌窦及上颌骨进行分割并进行三维评估，采用配对t检验进行比较。进行多元线性回归分析以研究缺损侧上颌窦与上颌骨的形态关系。
缺损侧与非缺损侧上颌窦的任何参数均无统计学显著差异（P>0.05）。缺损侧与非缺损侧上颌骨的长度、前宽度、前高度和体积存在显著差异（P<0.05）。上颌窦参数与缺损侧上颌骨的后宽度和高度显著相关。
UCLP青少年患者两侧上颌窦的3D结构特征相似。缺损侧与非缺损侧上颌骨在缺损相邻区域存在显著差异，但在上颌骨后部未显示。上颌骨后部的某些结构导致了上颌窦的变异。
