Department of Biological and Health Sciences, Federal University of Amapá, Macapá, Amapá, Brazil.
Department of Biological and Health Sciences, Federal University of Amapá, Macapá, Amapá, Brazil.
Arch Gerontol Geriatr. 2020 Jul-Aug;89:104082. doi: 10.1016/j.archger.2020.104082. Epub 2020 Apr 20.
To compare obtained and predicted inspiratory and expiratory muscle strength between frail, pre-frail, and non-frail older people; to examine the association between inspiratory and expiratory muscle strength and frailty in older people; and to determine cut-off points for inspiratory and expiratory muscle strength for discriminating frailty in older people.
A cross-sectional study was conducted with 379 community-dwelling older adults. Frailty was assessed using Fried's phenotype, while inspiratory and expiratory muscle strength were measured with maximum inspiratory and maximum expiratory pressures. Inferential analyses were performed using paired Student t-tests, one-way analysis of variance (ANOVA) tests, and a multinomial logistic regression model. ROC curves were constructed to establish cut-off points of maximum inspiratory and expiratory pressures for discriminating frailty and pre-frailty.
Frail and pre-frail participants presented significantly lower mean inspiratory and expiratory pressures compared to non-frail participants; values were significantly lower than predicted. Inspiratory and expiratory muscle strength were inversely associated with frailty and pre-frailty. Cut-off points ≥-50cmHO and ≤60cmHO for maximum inspiratory and expiratory pressures, respectively, were established as optimal discriminators of frailty. The cut-off point ≤65cmHO for maximum expiratory pressure was established as a discriminant for the presence of pre-frailty.
Inspiratory and expiratory muscle strength were lower in frail than in pre-frail older adults, and lower in pre-frail than in non-frail peers. Frailty and pre-frailty were inversely associated with inspiratory and expiratory muscle strength. Cut-off points for inspiratory and expiratory muscle strength may be useful in clinical practice for discriminating frailty and pre-frailty in older adults.
比较虚弱、衰弱前期和非虚弱老年人的吸气和呼气肌肉力量的实测值与预测值；探讨老年人吸气和呼气肌肉力量与虚弱的关系；确定吸气和呼气肌肉力量的截断值，以区分老年人的虚弱状态。
采用横断面研究方法，纳入 379 名社区居住的老年人。采用弗莱德表型评估虚弱，使用最大吸气压力和最大呼气压力测量吸气和呼气肌肉力量。采用配对学生 t 检验、单因素方差分析和多项逻辑回归模型进行推断性分析。构建 ROC 曲线，确定最大吸气和呼气压力的截断值，以区分虚弱和衰弱前期。
虚弱和衰弱前期参与者的平均吸气和呼气压力明显低于非虚弱参与者，实测值明显低于预测值。吸气和呼气肌肉力量与虚弱和衰弱前期呈负相关。最大吸气压力≥-50cmHO 和最大呼气压力≤60cmHO 分别作为区分虚弱的最佳截断值，最大呼气压力≤65cmHO 作为区分衰弱前期的截断值。
虚弱老年人的吸气和呼气肌肉力量明显低于衰弱前期老年人，衰弱前期老年人的吸气和呼气肌肉力量明显低于非虚弱老年人。虚弱和衰弱前期与吸气和呼气肌肉力量呈负相关。吸气和呼气肌肉力量的截断值可能有助于临床实践中区分老年人的虚弱和衰弱前期。
