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阻塞性睡眠呼吸暂停患者呼吸肌训练的有效性:一项系统评价与荟萃分析方案

Effectiveness of respiratory muscle training for patients with obstructive sleep apnea: A protocol of systematic review and meta-analysis.

作者信息

Xue Shi-Min, Jia Juan, Fan Ping, He Shi-Wei

机构信息

Department of Respiratory Medicine, Yulin No. 2 Hospital, Yulin, Shaanxi 719000.

Department of Nephrology, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi 710003.

出版信息

Medicine (Baltimore). 2020 May;99(20):e20309. doi: 10.1097/MD.0000000000020309.

Abstract

BACKGROUND

This study will evaluate the effectiveness and safety of respiratory muscle training (RMT) for patients with obstructive sleep apnea (OSA).

METHODS

Randomized controlled trials will be retrieved through electronic database searches from MEDLINE, EMBASE, Cochrane Library, CINAHL, Scopus, CBM, and CNKI from the beginning to the present. All electronic databases will be searched without any language limitation. Two researchers will independently select studies, collect data, and assess study quality, respectively. RevMan 5.3 software will be used for statistical analysis.

RESULTS

The primary outcome is severity of OSA, as measured by polysomnography or any relevant tools. The secondary outcomes are hypopnea index, apnea index, respiratory event index, respiratory disturbance index, sleep-related quality of life, and any expected or unexpected adverse events.

CONCLUSION

The results of this study will summarize current evidence of RMT for the treatment of patients with OSA.

SYSTEMATIC REVIEW REGISTRATION

INPLASY202040051.

摘要

背景

本研究将评估呼吸肌训练(RMT)对阻塞性睡眠呼吸暂停(OSA)患者的有效性和安全性。

方法

通过电子数据库检索从开始到目前来自MEDLINE、EMBASE、Cochrane图书馆、CINAHL、Scopus、CBM和CNKI的随机对照试验。所有电子数据库将无语言限制地进行检索。两名研究人员将分别独立选择研究、收集数据并评估研究质量。将使用RevMan 5.3软件进行统计分析。

结果

主要结局是通过多导睡眠图或任何相关工具测量的OSA严重程度。次要结局是呼吸暂停低通气指数、呼吸暂停指数、呼吸事件指数、呼吸紊乱指数、睡眠相关生活质量以及任何预期或意外的不良事件。

结论

本研究结果将总结RMT治疗OSA患者的当前证据。

系统评价注册

INPLASY202040051。

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