Kuwahara Takamichi, Hara Kazuo, Mizuno Nobumasa, Haba Shin, Okuno Nozomi
Department of Gastroenterology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
J Med Ultrason (2001). 2020 Jul;47(3):413-420. doi: 10.1007/s10396-020-01026-6. Epub 2020 May 22.
Ultrasound elastography is a relatively new diagnostic technique for measuring tissue elasticity (hardness). This review describes the types and evaluation methods of elastographies used in diagnosing pancreatic tumors. It also evaluates the diagnostic ability of transabdominal (US) or endoscopic ultrasonography (EUS) elastography for pancreatic tumors, based on findings from a search of published articles. Twenty articles (2096 cases) were selected from the databases. The types of elastography used for the diagnosis of pancreatic tumors were strain elastography and shear wave elastography. The evaluation methods of elastography and their diagnostic abilities (sensitivity and specificity) were 0.78 (95% confidence interval 0.65-0.87) and 0.82 (0.63-0.94) for color pattern diagnosis (US), 0.82 (0.77-0.86) and 0.70 (0.64-0.76) for color pattern diagnosis (EUS), 0.94 (0.90-0.97) and 0.87 (0.81-0.92) for strain ratio (EUS), 0.92 (0.90-0.94) and 0.79 (0.75-0.82) for histogram analysis (EUS), and 0.90 (0.82-0.95) and 0.82 (0.57-0.72) for shear wave elastography. In conclusion, there are many types of elastographies and evaluation methods, and the diagnostic ability for pancreatic tumors is high for each evaluation method.
超声弹性成像术是一种相对较新的用于测量组织弹性（硬度）的诊断技术。本综述描述了用于诊断胰腺肿瘤的弹性成像类型及评估方法。基于对已发表文章的检索结果，还评估了经腹超声（US）或内镜超声（EUS）弹性成像对胰腺肿瘤的诊断能力。从数据库中选取了20篇文章（共2096例病例）。用于诊断胰腺肿瘤的弹性成像类型有应变弹性成像和剪切波弹性成像。弹性成像的评估方法及其诊断能力（敏感性和特异性）分别为：彩色模式诊断（US）的敏感性为0.78（95%置信区间0.65 - 0.87），特异性为0.82（0.63 - 0.94）；彩色模式诊断（EUS）的敏感性为0.82（0.77 - 0.86），特异性为0.70（0.64 - 0.76）；应变率（EUS）的敏感性为0.94（0.90 - 0.97），特异性为0.87（0.81 - 0.92）；直方图分析（EUS）的敏感性为0.92（0.90 - 0.94），特异性为0.79（0.75 - 0.82）；剪切波弹性成像的敏感性为0.90（0.82 - 0.95），特异性为0.82（0.57 - 0.72）。总之，弹性成像类型和评估方法众多，且每种评估方法对胰腺肿瘤的诊断能力都很高。
