Hendaus Mohamed A, Jomha Fatima A
Department of Pediatrics, Sidra Medicine and Research Center, Doha, Qatar.
Weill Cornell Medicine, Ar-Rayyan, Qatar.
J Biomol Struct Dyn. 2021 Jul;39(11):4185-4191. doi: 10.1080/07391102.2020.1772110. Epub 2020 Jun 9.
Viral respiratory infections are very common and they are frequently eliminated from the body without any detrimental consequences. Secondary serious bacterial infection has been an apprehension expressed by health care providers, and this fear has been exacerbated in the era of Covid-19. Several published studies have shown an association between Covid-19 illness and secondary bacterial infection. However, the proposed mechanism by which a virus can develop a secondary bacterial infection is not well delineated. The aim of this commentary is to update the current evidence of the risk of bacterial infection in patients with Covid-19. We present several clinical studies related to the topic as well as a brief review of the potential pathophysiology of secondary infections that could present with Covid-19.Communicated by Ramaswamy H. Sarma.
病毒性呼吸道感染非常常见,它们通常会在没有任何不良后果的情况下从体内清除。继发性严重细菌感染一直是医疗保健提供者所担心的问题,在新冠疫情时代,这种担忧进一步加剧。多项已发表的研究表明,新冠疾病与继发性细菌感染之间存在关联。然而,病毒引发继发性细菌感染的具体机制尚未完全明确。本评论的目的是更新有关新冠患者发生细菌感染风险的现有证据。我们介绍了几项与该主题相关的临床研究,并简要回顾了可能与新冠相关的继发性感染的潜在病理生理学。由拉马斯瓦米·H·萨尔马传达。