Department of Neurosurgery, Athens Medical Center, Athens, Greece; Department of Neurosurgery, Apollonion Hospital, Nicosia, Cyprus; School of Medicine, European University Cyprus, Nicosia, Cyprus.
School of Medicine, European University Cyprus, Nicosia, Cyprus.
Injury. 2020 Dec;51 Suppl 4:S93-S95. doi: 10.1016/j.injury.2020.03.048. Epub 2020 May 16.
Dysfunction of the facial nerve is frequently attributed to inflammation, followed by traumatic injury. Knowledge of the complex anatomical course of the facial nerve is critical to localize the site of pathology and for successful management. The multiplicity of etiologies and its complex anatomy often make facial paralysis a diagnostic challenge. Neoplasms are a fairly rare cause of peripheral facial palsy, and are frequently overlooked in search of the more frequent traumatic or inflammatory etiologies of facial paralysis. Isolated metastatic lesions to the cerebellopontine angle (CPA) and internal auditory canal (IAC) are extremely rare. Their accurate diagnosis is difficult, since they share common clinical and radiological characteristics with vestibular schwannomas. We report a case of a 63-year-old female with a rapidly progressive left-sided hearing loss and complete facial palsy. Magnetic resonance imaging revealed a left intrameatal lesion. A provisional diagnosis of intracanalicular schwannoma or meningioma was made, although the possibility of metastasis due to her rapid neurological deterioration was considered. The patient underwent a translabyrinthine complete removal of the tumor followed by facial nerve reconstruction. The final histopathological findings revealed a metastatic breast adenocarcinoma. To our knowledge only seven prior cases of an isolated metastatic CPA lesion have been reported. In patients without a known malignancy, a rapid progression of hearing loss, disequilibrium, and facial palsy might be the first sign of a metastatic CPA lesion.
面神经功能障碍通常归因于炎症,其次是创伤性损伤。对面神经复杂解剖结构的了解对于定位病变部位和成功管理至关重要。多种病因及其复杂的解剖结构常常使面神经麻痹成为诊断挑战。肿瘤是引起周围性面神经麻痹的一个相当罕见的原因,在寻找面神经麻痹更常见的创伤性或炎症性病因时,常常被忽视。孤立的桥小脑角(CPA)和内听道(IAC)转移瘤极其罕见。由于它们与前庭神经鞘瘤具有共同的临床和影像学特征,因此准确诊断非常困难。我们报告了一例 63 岁女性,表现为左侧进行性听力损失和完全性面瘫。磁共振成像显示左侧内听道病变。初步诊断为内听道神经鞘瘤或脑膜瘤,但由于她的神经功能迅速恶化,也考虑到转移的可能性。患者接受了经迷路完全切除肿瘤和面神经重建。最终的组织病理学检查结果显示为转移性乳腺腺癌。据我们所知,仅有 7 例孤立性转移性 CPA 病变的病例报告。在没有已知恶性肿瘤的患者中,听力损失、平衡障碍和面瘫的快速进展可能是转移性 CPA 病变的第一个迹象。