溃疡性结肠炎相关的食管溃疡：病例系列与文献综述

Esophageal Ulcers Associated with Ulcerative Colitis: A Case Series and Literature Review.

作者信息

Tominaga Kentaro, Tsuchiya Atsunori, Sato Hiroki, Mizusawa Takeshi, Morita Shinichi, Ishii Yui, Takeda Nobutaka, Natsui Kazuki, Kawata Yuzo, Kimura Naruhiro, Arao Yoshihisa, Takahashi Kazuya, Hayashi Kazunao, Yokoyama Junji, Terai Shuji

机构信息

Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Japan.

Department of Gastroenterology and Hepatology, Uonuma Kikan Hospital, Japan.

出版信息

Intern Med. 2020 Aug 15;59(16):1983-1989. doi: 10.2169/internalmedicine.4437-20. Epub 2020 May 23.

DOI:10.2169/internalmedicine.4437-20

PMID:32448835

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7492127/

Abstract

Ulcerative colitis, a chronic and recurrent inflammatory disease, is localized to the colonic mucosa but can affect other organs and lead to various complications. Gastroduodenitis associated with ulcerative colitis has been reported. However, little is known about esophageal ulcers. We herein report two rare cases of esophageal ulcers associated with ulcerative colitis. Furthermore, the clinical and histological characteristics of 18 previously reported cases are summarized. This case series and literature review will encourage the accurate diagnosis and treatment of esophageal ulcers associated with ulcerative colitis.

摘要

溃疡性结肠炎是一种慢性复发性炎症性疾病，局限于结肠黏膜，但可累及其他器官并导致各种并发症。已有报道溃疡性结肠炎相关的胃十二指肠炎症。然而，关于食管溃疡的了解甚少。我们在此报告两例罕见的溃疡性结肠炎相关食管溃疡病例。此外，还总结了之前报道的18例病例的临床和组织学特征。本病例系列及文献综述将有助于促进溃疡性结肠炎相关食管溃疡的准确诊断和治疗。