Stewart Luke, Pearce Benjamin J, Beck Adam W, Spangler Emily L
Division of Vascular Surgery and Endovascular Therapy, 9968University of Alabama at Birmingham, AL, USA.
Vascular. 2020 Dec;28(6):739-746. doi: 10.1177/1708538120927704. Epub 2020 May 25.
Vein conduit is known to have better patency than prosthetic for infrainguinal bypass. Here we explore if racial disparities exist in infrainguinal bypass vein conduit use amid preoperative patient and systemic factors.
Retrospective Society for Vascular Surgery Vascular Quality Initiative data for 23,959 infrainguinal bypasses between 2003 and 2017 for occlusive disease were analyzed. For homogeneity, only infrainguinal bypasses originating from the common femoral artery were included. Demographics of patients receiving vein vs prosthetic were compared and logistic regression analyses were performed with race and preoperative factors to evaluate for predictors of vein conduit use.
Adjusted regression models demonstrated black patients were 76% as likely ( < .001) and Hispanic patients 79% as likely ( = .003) to have vein conduit compared to white patients. Factors positively correlating with vein use included vein mapping, more distal bypass target, tissue loss or acute ischemia bypass indications, commercial insurance, and weight. Factors against vein use included advanced age, female gender, ASA class 4, urgent procedure, preoperative mobility limitation, prior CABG or leg bypass, prior smoking, preoperative anticoagulation, and a bypass performed in the Southern US or before 2012. While black and Hispanic patients were less likely to receive vein, they were vein mapped at similar or higher rates than other groups.
Racial disparities exist in conduit use for infrainguinal bypass, with black and Hispanic patients less likely to receive vein bypasses. However, the contribution of race to conduit selection is small in adjusted and unadjusted models. Overall, pre-operative variables in the Vascular Quality Initiative poorly predicted vein conduit use for infrainguinal bypass.
在下肢旁路手术中,静脉移植物的通畅率优于人工血管。在此,我们探讨在术前患者和全身因素的影响下,下肢旁路手术中静脉移植物的使用是否存在种族差异。
对2003年至2017年间血管外科学会血管质量倡议组织的23959例下肢闭塞性疾病旁路手术的回顾性数据进行分析。为保持同质性,仅纳入源自股总动脉的下肢旁路手术。比较接受静脉移植物和人工血管患者的人口统计学特征,并对种族和术前因素进行逻辑回归分析,以评估静脉移植物使用的预测因素。
校正回归模型显示,与白人患者相比,黑人患者使用静脉移植物的可能性为76%(<0.001),西班牙裔患者为79%(=0.003)。与静脉移植物使用呈正相关的因素包括静脉造影、更远端的旁路目标、组织缺失或急性缺血旁路指征、商业保险和体重。不利于静脉移植物使用的因素包括高龄、女性、美国麻醉医师协会分级4级、急诊手术、术前活动受限、既往冠状动脉搭桥术或下肢旁路手术、既往吸烟、术前抗凝以及在美国南部或2012年之前进行的旁路手术。虽然黑人和西班牙裔患者接受静脉移植物的可能性较小,但他们接受静脉造影的比例与其他组相似或更高。
下肢旁路手术中移植物的使用存在种族差异,黑人和西班牙裔患者接受静脉旁路手术的可能性较小。然而,在校正和未校正模型中,种族对移植物选择的影响较小。总体而言,血管质量倡议组织中的术前变量对下肢旁路手术中静脉移植物使用的预测能力较差。