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用于生物成像应用的菁类硼酸衍生的水杨醛缩肼配合物(Cy-BASHY)。

Cyanine-Like Boronic Acid-Derived Salicylidenehydrazone Complexes (Cy-BASHY) for Bioimaging Applications.

机构信息

Research Institute for Medicines (iMed.ULisboba), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.

CIQSO-Centre for Research in Sustainable Chemistry and Department of, Chemistry, University of Huelva, Campus de El Carmen s/n, 21071, Huelva, Spain.

出版信息

Chemistry. 2020 Nov 6;26(62):14064-14069. doi: 10.1002/chem.202001623. Epub 2020 Oct 1.

Abstract

Boronic acid-derived salicylidenehydrazone complex (BASHY) dyes with a polymethine backbone were designed to yield efficient red-emitting and two-photon absorbing fluorophores that can be used as markers for astrocytes. The dyes are chemically stable in aqueous solution and do not undergo photodecomposition. Their photophysical properties can be electronically fine-tuned and thereby adapted to potentially different imaging situations and requirements.

摘要

硼酸衍生的水杨醛缩腙配合物(BASHY)染料具有聚甲川骨架,旨在产生高效的红色发射和双光子吸收荧光团,可作为星形胶质细胞的标记物。染料在水溶液中化学稳定,不会发生光分解。它们的光物理性质可以进行电子微调,从而适应潜在的不同成像情况和要求。

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