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[中国仓鼠V79-4细胞在热疗与放疗联合作用后的活力恢复]

[Recovery of the viability of Chinese hamster V79-4 cells after combined exposure to hyperthermia and radiation].

作者信息

Nasonova E A, Glazunov A V

出版信息

Tsitologiia. 1988 Oct;30(10):1273-6.

PMID:3245095
Abstract

The survival of cells overheated (42 degrees C) before gamma irradiation is increased by holding them in the growth medium at 37 degrees C before treatment with hypertonic NaCl solution. The substantial synergistic effect of hyperthermia and radiation takes place when the cells are treated with a 1.5 M NaCl solution immediately after the combined action of these inactivating factors. The synergistic effect is decreased by holding the cells in the nutrient medium at 37 degrees C for 4 hours before hypertonic treatment.

摘要

在γ射线照射前过热(42摄氏度)的细胞,在使用高渗氯化钠溶液处理前于37摄氏度的生长培养基中保存,其存活率会提高。当细胞在这些灭活因子联合作用后立即用1.5M氯化钠溶液处理时,热疗和辐射会产生显著的协同效应。在高渗处理前将细胞于37摄氏度的营养培养基中保存4小时,协同效应会降低。

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