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在氨甲环酸时代,初次全髋关节和全膝关节置换术是否还需要进行血型和配血检查?

In the Era of Tranexamic Acid, are Type and Screens for Primary Total Joint Arthroplasty Obsolete?

机构信息

OrthoCarolina Hip and Knee Center, Charlotte, NC.

OrthoCarolina Research Institute, Charlotte, NC.

出版信息

J Arthroplasty. 2020 Sep;35(9):2363-2366. doi: 10.1016/j.arth.2020.04.056. Epub 2020 Apr 25.

Abstract

BACKGROUND

Advances in technique and perioperative blood management have improved transfusion rates following unilateral primary total joint arthroplasty and led some centers to change their preoperative blood ordering protocols. The purpose of this study is to determine whether deleting type and screens (T&S) from preoperative order sets was safe for patients undergoing primary total knee (TKA) and total hip arthroplasty (THA) and to identify patients who required allogenic blood transfusion.

METHODS

Prospectively collected data were reviewed to identify any patient with a hemoglobin (Hgb) drawn within 30 days of surgery who received a transfusion following a unilateral primary TKA or THA.

RESULTS

A total of 1255 patients met inclusion criteria. Of the total, 682 (54%) were TKAs and 573 (46%) were THAs. The mean preoperative Hgb was 11.5 g/dL with an average delta Hgb of 3.6 g/dL on postoperative day 1. No patient required an intraoperative transfusion. Fourteen patients (mean age and body mass index, 67.9 and 29.0) required a transfusion (1.1%) for postoperative blood loss anemia. Of those transfused, 13 (93%) of the patients underwent THA with the mean estimated blood loss of 378.6 mL. The total cost for a patient obtaining a T&S is $191.27.

CONCLUSION

In our series, the risk of blood transfusion was rare (1.1%) and occurred only secondary to postoperative blood loss anemia. There were no cases of intraoperative complication requiring urgent or emergent blood transfusion. Removing T&S from standard order sets for patients undergoing primary TKA or THA appears to be a safe and cost-effective practice.

摘要

背景

技术和围手术期血液管理的进步提高了单侧初次全关节置换术后的输血率,并促使一些中心改变了术前的血液订购方案。本研究的目的是确定在接受初次全膝关节置换术(TKA)和全髋关节置换术(THA)的患者中,从术前医嘱集删除血型和筛查(T&S)是否安全,并确定需要异体输血的患者。

方法

前瞻性收集的数据进行了回顾,以确定在手术前 30 天内抽取血红蛋白(Hgb)并在单侧初次 TKA 或 THA 后接受输血的任何患者。

结果

共有 1255 名患者符合纳入标准。其中 682 例(54%)为 TKA,573 例(46%)为 THA。术前平均 Hgb 为 11.5 g/dL,术后第 1 天平均 Hgb 下降 3.6 g/dL。无患者需要术中输血。14 名患者(平均年龄和体重指数分别为 67.9 和 29.0)因术后失血贫血需要输血(1.1%)。在接受输血的患者中,有 13 名(93%)患者接受了 THA,平均估计失血量为 378.6 毫升。患者进行 T&S 检查的总费用为 191.27 美元。

结论

在我们的系列中,输血的风险很低(1.1%),且仅继发于术后失血贫血。没有因术中并发症需要紧急或紧急输血的病例。对于接受初次 TKA 或 THA 的患者,从标准医嘱集中删除 T&S 似乎是一种安全且具有成本效益的做法。

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