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球囊辅助超声引导下经皮注射凝血酶治疗医源性股动脉假性动脉瘤:病例报告及技术描述

Balloon-Assisted Ultrasound-Guided Percutaneous Thrombin Injection of Iatrogenic Femoral Artery Pseudoaneurysms: A Case Report and Description of the Technique.

作者信息

Vowels Travis J, Zubair M Mujeeb, Bismuth Jean, Le Linda

机构信息

Department of Cardiovascular Surgery, Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX, USA.

出版信息

Vasc Endovascular Surg. 2020 Aug;54(6):532-535. doi: 10.1177/1538574420927861. Epub 2020 May 26.

DOI:10.1177/1538574420927861
PMID:32452286
Abstract

Ultrasound-guided thrombin injection (UGTI) has emerged as the first-line treatment for moderately sized or persistent pseudoaneurysms (PSAs). Although rare, the most feared complication of UGTI is arterial thrombosis or embolism during the off-label injection of thrombin causing acute limb ischemia requiring emergent surgical intervention. Higher thrombin volume, rapidity of injection, and wide or short-neck PSAs are all thought to increase the risk of arterial thrombosis or embolism during this procedure. For patients with unfavorable PSA anatomy who are high-risk surgical candidates due to their medical comorbidities or active critical illness, balloon-assisted thrombin injection (BATI) has been suggested as a means to potentially reduce the risk of thrombosis or distal embolization associated with UGTI. This minimally invasive technique also decreases the risk of groin wound dehiscence or infection associated with open repair, especially in patients who are morbidly obese or have had prior groin surgery. We report a patient with a complex femoral artery PSA after endovascular intervention who was successfully treated with BATI and describe the procedure in detail.

摘要

超声引导下凝血酶注射(UGTI)已成为中等大小或持续性假性动脉瘤(PSA)的一线治疗方法。尽管罕见,但UGTI最可怕的并发症是在凝血酶超适应证注射期间发生动脉血栓形成或栓塞,导致急性肢体缺血,需要紧急手术干预。较高的凝血酶体积、注射速度以及宽颈或短颈PSA都被认为会增加该过程中动脉血栓形成或栓塞的风险。对于因内科合并症或严重危重病而成为高风险手术候选者的PSA解剖结构不佳的患者,有人建议采用球囊辅助凝血酶注射(BATI),作为一种可能降低与UGTI相关的血栓形成或远端栓塞风险的方法。这种微创技术还降低了与开放修复相关的腹股沟伤口裂开或感染的风险,特别是在病态肥胖或既往有腹股沟手术史的患者中。我们报告了1例血管内介入治疗后出现复杂股动脉PSA的患者,其成功接受了BATI治疗,并详细描述了该操作过程。

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