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迈向第二代灭活疫苗。使用疱疹病毒(猫鼻气管炎病毒)亚单位预防猫流感。

Towards a second generation of inactivated vaccines. Use of herpesvirus (feline rhinotracheitis virus) subunits for the prevention of cat flu.

作者信息

Saint-Gérand A L

机构信息

Rhône Mérieux, Lyon, France.

出版信息

Vaccine. 1988 Dec;6(6):468-9. doi: 10.1016/0264-410x(88)90092-8.

Abstract

Prevention of feline upper respiratory disease, commonly known as 'cat flu' is traditionally achieved by two types of vaccination: live vaccines administered by intranasal or by parenteral inoculation or parenteral inactivated vaccines with an adjuvant. Both of these have been associated with side effects. The objective of the development of a new generation of cat flu vaccines was to market a vaccine which was perfectly safe in all epidemiological situations and was as potent as the current products available on the market.

摘要

预防猫上呼吸道疾病,通常称为“猫流感”,传统上是通过两种疫苗接种来实现的:通过鼻内或肠胃外接种的活疫苗,或带有佐剂的肠胃外灭活疫苗。这两种疫苗都有副作用。新一代猫流感疫苗的研发目标是推出一种在所有流行病学情况下都完全安全且与市场上现有产品效力相当的疫苗。

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