Jäger J, Kunze P
Pathologisches Institut, Zentralklinik für Herz- und Lungenkrankheiten Bad Berka.
Zentralbl Allg Pathol. 1988;134(7):681-6.
In some cases of achalasia, lungs may show characteristic granulomatous pneumonia, following non-symptomatic spill-over and aspiration of fat. The lesion is characterised by fat-containing vacuoles, necrosis, granulocytes, macrophages, some of them with lipid content, epithelioid and giant cells and fibrosis rich in lymphocytes. The histological pattern is pathognomonic and represents an entity. These alterations may be mistaken for tuberculosis and be distinguished from mineral-oil pneumonia (paraffinoma). Affected lung regions may be colonised by nontuberculous (atypical) mycobacteria.
在某些贲门失弛缓症病例中，肺部可能会出现特征性的肉芽肿性肺炎，这是在脂肪无症状溢出和误吸之后发生的。病变的特征为含有脂肪的空泡、坏死、粒细胞、巨噬细胞（其中一些含有脂质）、上皮样细胞和巨细胞以及富含淋巴细胞的纤维化。组织学模式具有诊断特异性，代表一种独立的病症。这些改变可能被误诊为肺结核，并与矿物油肺炎（石蜡瘤）相区分。受影响的肺区域可能会被非结核（非典型）分枝杆菌定植。
