Department of Endocrinology, The Second Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi, China.
Department of Pulmonary and Critical Care Medicine, The Second People's Hospital of Jingdezhen, Jingdezhen 100191, Jiangxi, China.
Aging (Albany NY). 2020 May 26;12(10):9440-9446. doi: 10.18632/aging.103217.
Several studies have shown that active smoking is a risk factor for type 2 diabetes mellitus (T2DM). However, the effects of passive smoking on T2DM remains unknown. In this study, we investigated the effects of passive smoking and its duration on the prevalence of prediabetes and T2DM. According to passive smoking status, participants were divided into Group A (passive smokers) and Group B (controls). Furthermore, Group A was divided into three subgroups according to the duration of passive smoking: Group A1 (≤10 years), Group A2 (10-20 years), and Group A3 (>20 years). We found that the prevalence of impaired glucose tolerance (IGT) in Group A (26.6%), Group A2 (28%), and Group A3 (37.8%) was significantly higher than that in Group B (19.6%), and the prevalence gradually increased with an increase in the duration of passive smoking. Multiple logistic regression analysis showed that passive smoking for >10 years was a risk factor for impaired fasting glucose (IFG), IGT, and T2DM. Therefore, passive smoking not only increases the prevalence of IGT in a time-dependent manner, but also a risk factor for IFG, IGT, and T2DM when its duration is over 10 years.
多项研究表明,主动吸烟是 2 型糖尿病(T2DM)的一个危险因素。然而,被动吸烟对 T2DM 的影响尚不清楚。本研究旨在探讨被动吸烟及其持续时间对糖尿病前期和 T2DM 患病率的影响。根据被动吸烟状况,将参与者分为 A 组(被动吸烟者)和 B 组(对照组)。此外,根据被动吸烟的持续时间,将 A 组进一步分为 A1 组(≤10 年)、A2 组(10-20 年)和 A3 组(>20 年)。结果发现,A 组(26.6%)、A2 组(28%)和 A3 组(37.8%)的葡萄糖耐量受损(IGT)患病率明显高于 B 组(19.6%),且随着被动吸烟持续时间的增加,患病率逐渐升高。多因素 logistic 回归分析显示,被动吸烟>10 年是空腹血糖受损(IFG)、IGT 和 T2DM 的危险因素。因此,被动吸烟不仅会使 IGT 的患病率呈时间依赖性增加,而且当持续时间超过 10 年时,也是 IFG、IGT 和 T2DM 的危险因素。