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尼日利亚南南地区瓦里市产前检查人群中孕期贫血的患病率、严重程度及相关因素:一项基于医院的横断面研究

Prevalence, Severity, and Correlates of Anaemia in Pregnancy among Antenatal Attendees in Warri, South-Southern Nigeria: A Cross-Sectional and Hospital-Based Study.

作者信息

Omote Victor, Ukwamedua Henry Awele, Bini Nathaniel, Kashibu Emmanuel, Ubandoma Joel Rimamnde, Ranyang Akafa

机构信息

Department of Laboratory Services, Central Hospital Warri, Warri, Nigeria.

Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, Ambrose Alli University, Ekpoma, Nigeria.

出版信息

Anemia. 2020 May 8;2020:1915231. doi: 10.1155/2020/1915231. eCollection 2020.

Abstract

INTRODUCTION

Anaemia in pregnancy affects about half of all pregnant women globally and constitutes an important reproductive health issue. The World Health Organization estimates that the prevalence of anaemia in pregnancy varies from 53.8% to 90.2% in developing countries and 8.3% to 23% in developed countries. Anaemia in pregnancy is common in developing countries and prevalence statistics required for its effective management and control is not adequately available in Nigeria. Thus, this study seeks to provide prevalence statistics of anaemia in pregnancy for the study region and its severity and highlight some possible correlates.

METHODS

A total of 218 pregnant women were recruited from the antenatal clinic of Central Hospital Warri using simple random technique after approval from the institutional review board and consent from the participants. Data on sociodemographics, economic status, and clinical history were collected using a pretested structured interviewer's questionnaire. Participant's haematocrit levels were estimated using standard laboratory techniques and anaemia was diagnosed using WHO-recommended cutoff.

RESULTS

The overall prevalence of anaemia was 37.6%. This prevalence dropped to 10.6% when a cutoff of less than 30% haematocrit was used. There was a direct relationship between haematocrit values and the participants' age while mild anaemia accounted for the bulk (72%) of the anaemic cases. Participants younger than 20 years of age gave the highest age-based prevalence while parity-based prevalence was even among subgroups. Participants without formal education and those who were unemployed accounted for the highest prevalence in their different categories.

CONCLUSION

Based on the findings from our study, anaemia in pregnancy is still of primary public health concern if WHO cutoff is used for the diagnosis. However, the reduction observed when less than 30% haematocrit was used tags our study zone to be of moderate severity. Although all variables lacked statistical significance, younger age, no formal education, and unemployment were highlighted to be predisposing factors.

摘要

引言

全球约有一半的孕妇受孕期贫血影响,这是一个重要的生殖健康问题。世界卫生组织估计,发展中国家孕期贫血患病率在53.8%至90.2%之间,发达国家则在8.3%至23%之间。孕期贫血在发展中国家很常见,而尼日利亚缺乏有效管理和控制所需的患病率统计数据。因此,本研究旨在提供研究区域孕期贫血的患病率统计数据及其严重程度,并突出一些可能的相关因素。

方法

经机构审查委员会批准并获得参与者同意后,采用简单随机技术从瓦里中央医院的产前诊所招募了218名孕妇。使用预先测试的结构化访谈问卷收集社会人口统计学、经济状况和临床病史数据。采用标准实验室技术估计参与者的血细胞比容水平,并使用世界卫生组织推荐的临界值诊断贫血。

结果

贫血的总体患病率为37.6%。当使用血细胞比容低于30%的临界值时,这一患病率降至10.6%。血细胞比容值与参与者年龄之间存在直接关系,轻度贫血占贫血病例的大部分(72%)。20岁以下的参与者基于年龄的患病率最高,而基于胎次的患病率在各亚组中相同。未受过正规教育和失业的参与者在各自类别中的患病率最高。

结论

根据我们的研究结果,如果使用世界卫生组织的临界值进行诊断,孕期贫血仍然是主要的公共卫生问题。然而,当使用低于30%的血细胞比容时观察到的患病率下降表明我们的研究区域贫血严重程度为中度。尽管所有变量均无统计学意义,但年龄较小、未受过正规教育和失业被认为是诱发因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3538/7232721/45078109fa3d/ANEMIA2020-1915231.001.jpg

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