Kondo K, Kamidono S, Hamami G
Department of Urology, Faculty of Medicine, Kobe University.
Hinyokika Kiyo. 1988 Oct;34(10):1845-51.
Iopamidol (Iopamiron 370) was examined for use in intravenous urography in 37 patients who previously developed adverse reactions to conventional ionic contrast media or had a history of allergy. The patients were divided into three groups (group A1:22 patients with previous adverse reactions to contrast media, but without history of allergy, group A2:8 patients with previous adverse reactions to contrast media and with history of allergy, group B:7 patients with a history of allergy, but without experience of using contrast media. Adverse reactions to iopamidol were observed in 6 patients (one in group A1, four in group A2, one in group B) and there were no serious adverse reactions. In conclusion, iopamidol seems to be a safe contrast medium for the patients without history of allergy, but we should examine it carefully as in the case of conventional ionic contrast media.
对37例既往对传统离子型造影剂出现不良反应或有过敏史的患者，使用碘帕醇（碘必乐370）进行静脉尿路造影检查。患者分为三组（A1组：22例既往对造影剂有不良反应但无过敏史；A2组：8例既往对造影剂有不良反应且有过敏史；B组：7例有过敏史但无造影剂使用经历）。6例患者出现碘帕醇不良反应（A1组1例，A2组4例，B组1例），无严重不良反应。总之，对于无过敏史的患者，碘帕醇似乎是一种安全的造影剂，但我们应像对待传统离子型造影剂那样仔细检查。
