amedes MVZ wagnerstibbe für Laboratoriumsmedizin, Hämostaseologie, Humangenetik und Mikrobiologie, Hannover, Germany.
Hamostaseologie. 2020 Jun;40(2):174-183. doi: 10.1055/a-1113-0689. Epub 2020 May 26.
Despite a lot of research on antiphospholipid antibodies (aPL), standardization of test systems, and better definition of its clinical symptoms, the pathomechanism of this acquired autoimmune disease is not yet fully explained. Progress in treatment increased the live birth rate in 70 to 80% of women suffering from obstetric antiphospholipid syndrome (OAPS). However, still 20 to 30% will develop adverse pregnancy outcome. Lack of awareness of this disorder as the cause for pregnancy complications is very harmful to mothers and to their newborns. Complications can be avoided or minimized by proper treatment. The aim of this article is to increase the awareness of gynecologists and medical personal for OAPS.
尽管对抗磷脂抗体(aPL)进行了大量研究,对检测系统进行了标准化,并且对其临床症状进行了更好的定义,但这种获得性自身免疫性疾病的发病机制尚未完全阐明。治疗的进展使 70%至 80%患有产科抗磷脂综合征(OAPS)的女性的活产率有所提高。但是,仍有 20%至 30%会出现不良妊娠结局。如果不了解这种疾病是导致妊娠并发症的原因,对母亲及其新生儿是非常有害的。通过适当的治疗可以避免或最小化并发症。本文的目的是提高妇产科医生和医务人员对 OAPS 的认识。