Altini Corinna, Lavelli Valentina, Niccoli-Asabella Artor, Sardaro Angela, Branca Alessia, Santo Giulia, Ferrari Cristina, Rubini Giuseppe
Nuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza Giulio Cesare, 11-70124 Bari, Italy.
Nuclear Medicine Unit, AOU Policlinic "A. Perrino", 72100 Brindisi, Italy.
J Clin Med. 2020 May 22;9(5):1581. doi: 10.3390/jcm9051581.
Spondylodiscitis is a spine infection for which a diagnosis by a magnetic resonance imaging (MRI) is considered the most appropriate imaging technique. The aim of this study was to compare the role of an F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) and an MRI in this field. For 56 patients with suspected spondylodiscitis for whom MRI and F-FDG PET/CT were performed, we retrospectively analyzed the results. Cohen's was applied to evaluate the agreement between the two techniques in all patients and in subgroups with a different number of spinal districts analyzed by the MRI. Sensitivity, specificity, and accuracy were also evaluated. The agreements of the F-FDG PET/CT and MRI in the evaluation of the entire population, whole-spine MRI, and two-districts MRI were moderate ( = 0.456, = 0.432, and = 0.429, respectively). In patients for whom one-district MRI was performed, F-FDG PET/CT and MRI were both positive and completely concordant ( = 1). We also separately evaluated patients with suspected spondylodiscitis caused by Mycobacterium tuberculosis for whom the MRI and F-FDG PET/CT were always concordant excepting in 2 of the 18 (11%) patients. Sensitivity, specificity, and accuracy of the MRI and F-FDG PET/CT were 100%, 60%, 97%, and 92%, 100%, and 94%, respectively. Our results confirmed the F-FDG PET/CT diagnostic value in the diagnosis of spondylodiscitis is comparable to that of MRI for the entire spine evaluation. This could be considered a complementary technique or a valid alternative to MRI.
脊椎椎间盘炎是一种脊柱感染性疾病，对于该病，磁共振成像（MRI）诊断被认为是最合适的成像技术。本研究的目的是比较氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）和MRI在该领域的作用。对56例疑似脊椎椎间盘炎且接受了MRI和F-FDG PET/CT检查的患者，我们回顾性分析了结果。应用科恩系数评估两种技术在所有患者以及MRI分析的不同脊柱节段亚组中的一致性。还评估了敏感性、特异性和准确性。F-FDG PET/CT与MRI在评估整个人群、全脊柱MRI和两个节段MRI时的一致性为中等（分别为 = 0.456、= 0.432和 = 0.429）。在接受单节段MRI检查的患者中，F-FDG PET/CT和MRI均为阳性且完全一致（ = 1）。我们还分别评估了疑似由结核分枝杆菌引起的脊椎椎间盘炎患者，其中MRI和F-FDG PET/CT除18例中的2例（11%）外始终一致。MRI和F-FDG PET/CT的敏感性、特异性和准确性分别为100%、60%、97%和92%、100%、94%。我们的结果证实，F-FDG PET/CT在脊椎椎间盘炎诊断中的诊断价值与MRI在评估整个脊柱时相当。这可被视为一种补充技术或MRI的有效替代方法。
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