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[拜氏病:它是梅毒吗?]

[The Baie disease: was it syphilis?].

作者信息

LeBlond S

出版信息

Can Med Assoc J. 1977 Jun 4;116(11):1284-8, 1290.

Abstract

In 1773 an epidemic disease with cutaneous manifestations appeared in Baie Saint-Paul, Québec and spread rapidly from nearby les Eboulements to the entire island of Montreal. The epidemic was in many ways reminiscent of a typical outbreak of syphilis, a condition then well known in Europe. Dr. Charles Blake of Montreal, as well as Drs. James Bowman and Philippe Badelart of Quebec, would not acknowledge any other diagnosis. The latter two physicians were commissioned by General Haldimand, governor of Canada, to investigate and treat this new disease. Patients were often cured by potions or ointments containing mercury if used from the onset of symptoms. However, Dr. Robert Jones, another physician from Montreal, submitted a different opinion: the clinical course of the disease, the anomalies of its transmission, its sometimes intriguing sequelae and its unpredictable response to mercurial therapy led him to believe that it might be an entity entirely different from syphilis as it was then known in Europe. Half a century earlier, in Scotland, a similar outbreak had occurred for which the same reservation had been made with regard to a possible diagnosis of syphilis.

摘要

1773年,一种伴有皮肤症状的流行病在魁北克的圣保罗湾出现,并迅速从附近的勒布勒门蔓延至整个蒙特利尔岛。这场流行病在很多方面让人联想到典型的梅毒暴发,而梅毒在当时的欧洲是一种广为人知的疾病。蒙特利尔的查尔斯·布莱克医生,以及魁北克的詹姆斯·鲍曼医生和菲利普·巴德拉尔医生,都不承认有其他诊断结果。后两位医生受加拿大总督哈尔迪曼将军委托,对这种新疾病进行调查和治疗。如果在症状出现之初就使用含汞的药剂或药膏,患者往往能被治愈。然而,蒙特利尔的另一位医生罗伯特·琼斯医生却提出了不同意见:这种疾病的临床病程、传播异常情况、有时令人费解的后遗症以及对汞剂疗法不可预测的反应,使他认为这可能是一种与当时欧洲所知的梅毒完全不同的疾病。半个世纪前,在苏格兰也曾发生过类似的疫情,当时对于梅毒的可能诊断也存在同样的保留意见。

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