Department of Epidemiology and Biostatistics, School of Public health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
Department of Statistics, College of Natural and Computational Science, Debre Markos University, Debre Markos, Ethiopia.
BMC Infect Dis. 2020 May 27;20(1):380. doi: 10.1186/s12879-020-05106-3.
Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high and continuous as neglected tropical disease of resource-poor settings, and particularly affects young age groups. Despite of these facts, studies conducted in Ethiopia regarding to the prevalence and associated factors for scabies infestation have been highly variable and didn't well compiled. Due to that, the aim of this systematic review and meta-analysis was to estimates the overall prevalence of scabies and associated factors in all age groups in Ethiopia.
International databases (PubMed/PMC/Midline, EMBASE, CINAHL, Web of Science, Google Scholar, Google and Science Direct) were systematically searched from December 1, 2019, to January 18, 2020. All observational studies noted the prevalence of human scabies and associated factors in Ethiopia were included. Two authors (AG and G.T) independently extracted all necessary data using a standardized data extraction format. The data which is extracted each study were analyzed using STATA Version 14.1. Heterogeneity among the included studies was assessed through the Cochrane Q test statistics and I test. Lastly, a random effects meta-analysis model was computed to fix overall prevalence and associated factors of scabies.
Twelve studies were included in this meta-analysis after 410 articles retrieved. Of these, eight studies were analyzed for prevalence estimation. The overall prevalence of scabies infestation was 14.5% (95%CI: 1.5, 27.6%) in Ethiopia. Furthermore, the subgroup analysis revealed the highest prevalence was 19.6% in Amhara region. A person from a large family size (OR: 3.1, 95% CI: 1.76, 5.67), and sharing a bed (OR: 3.59, 95%CI: 2.88, 4.47) were significantly associated with scabies.
This study revealed the prevalence of scabies infestation was 14.5% in Ethiopia which was high. Persons from high family size and any contact with scabies case were factors associated with scabies.
疥疮是一种由疥螨引起的传染病，通过密切的个人接触传播。尽管它是一种容易治疗的疾病，但作为资源匮乏环境中的一种被忽视的热带病，它的流行率仍然很高且持续存在，尤其影响年轻人群。尽管如此，在埃塞俄比亚进行的关于疥疮感染的患病率和相关因素的研究结果差异很大，且没有很好地综合。因此，本系统评价和荟萃分析的目的是估计埃塞俄比亚所有年龄段人群中疥疮的总体患病率和相关因素。
从 2019 年 12 月 1 日至 2020 年 1 月 18 日，系统地检索了国际数据库（PubMed/PMC/Midline、EMBASE、CINAHL、Web of Science、Google Scholar、Google 和 Science Direct）。所有观察性研究均记录了埃塞俄比亚人类疥疮的患病率和相关因素。两位作者（AG 和 G.T）独立使用标准化数据提取格式提取所有必要数据。使用 Cochrane Q 检验统计量和 I 检验评估纳入研究之间的异质性。最后，使用随机效应荟萃分析模型计算固定总体患病率和疥疮的相关因素。
在检索到的 410 篇文章中，有 12 篇研究被纳入荟萃分析。其中，有 8 项研究用于估计患病率。埃塞俄比亚疥疮感染的总体患病率为 14.5%（95%CI：1.5，27.6%）。此外，亚组分析显示，阿姆哈拉地区的患病率最高，为 19.6%。来自大家庭的人（OR：3.1，95%CI：1.76，5.67）和共用床铺的人（OR：3.59，95%CI：2.88，4.47）与疥疮显著相关。
本研究显示，埃塞俄比亚的疥疮感染率为 14.5%，这一比例较高。来自大家庭的人和与疥疮病例有任何接触的人是与疥疮相关的因素。
