College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Debre Markos Referral Hospital, Debre Markos, Ethiopia.
PLoS One. 2018 Jun 28;13(6):e0199684. doi: 10.1371/journal.pone.0199684. eCollection 2018.
Despite remarkable progress in the reduction of under-five mortality, childhood diarrhea is still the leading cause of mortality and morbidity in this highly susceptible and vulnerable population. In Ethiopia, study findings regarding prevalence and determinants of diarrhea amongst under-five children have been inconsistent. Therefore, this systematic review and meta-analysis estimates the pooled prevalence of diarrhea and its determinants among under-five children in Ethiopia.
International databases, including PubMed, Web of Science, EMBASE, CINAHL, Google Scholar, Science Direct, and the Cochrane Library, were systematically searched. All identified observational studies reporting the prevalence and determinants of diarrhea among under-five children in Ethiopia were included. Two authors independently extracted all necessary data using a standardized data extraction format. STATA Version 13 statistical software was used. The Cochrane Q test statistics and I2 test were used to assess the heterogeneity of the studies. A random effects model was computed to estimate the pooled prevalence of diarrhea. Moreover, the associations between determinant factors and childhood diarrhea were examined using the random effect model.
After reviewing of 535 studies, 31studies fulfilled the inclusion criteria and were included in the meta-analysis. The findings from the 31 studies revealed that the pooled prevalence of diarrhea among under-five children in Ethiopia was 22% (95%CI: 19, 25%). Subgroup analysis of this study revealed that the highest prevalence was observed in Afar region (27%), followed by Somali and Dire Dawa regions (26%), then Addis Abeba (24%). Lack of maternal education (OR: 2.5, 95% CI: 1.3, 2.1), lack of availability of latrine (OR: 2.0, 95%CI: 1.3, 3.2), urban residence (OR: 1.9, 95%CI: 1.2, 3.0), and maternal hand washing (OR: 2.2, 95%CI: 2.0, 2.6) were significantly associated with childhood diarrhea.
In this study, diarrhea among under-five children in Ethiopia was significantly high. Lack of maternal education, lack of availability of latrine, urban residence, and lack of maternal hand washing were significantly associated with childhood diarrhea.
尽管在降低五岁以下儿童死亡率方面取得了显著进展,但儿童腹泻仍然是这一年龄段高度易感染和脆弱人群死亡和发病的主要原因。在埃塞俄比亚,关于五岁以下儿童腹泻的患病率和决定因素的研究结果一直不一致。因此,本系统评价和荟萃分析估计了埃塞俄比亚五岁以下儿童腹泻的总患病率及其决定因素。
系统检索了国际数据库,包括 PubMed、Web of Science、EMBASE、CINAHL、Google Scholar、Science Direct 和 Cochrane Library。纳入了所有报告埃塞俄比亚五岁以下儿童腹泻患病率和决定因素的观察性研究。两位作者使用标准化数据提取格式独立提取所有必要数据。使用 STATA 版本 13 统计软件。Cochrane Q 检验统计量和 I2 检验用于评估研究的异质性。使用随机效应模型计算腹泻的总患病率。此外,使用随机效应模型检查决定因素与儿童腹泻之间的关联。
在审查了 535 项研究后,有 31 项研究符合纳入标准并纳入荟萃分析。31 项研究的结果表明,埃塞俄比亚五岁以下儿童腹泻的总患病率为 22%(95%CI:19,25%)。本研究的亚组分析显示,患病率最高的是阿法尔地区(27%),其次是索马里和 Dire Dawa 地区(26%),然后是亚的斯亚贝巴(24%)。母亲教育程度低(OR:2.5,95%CI:1.3,2.1)、厕所不可用(OR:2.0,95%CI:1.3,3.2)、城市居住(OR:1.9,95%CI:1.2,3.0)和母亲洗手(OR:2.2,95%CI:2.0,2.6)与儿童腹泻显著相关。
在这项研究中,埃塞俄比亚五岁以下儿童腹泻的发生率明显较高。母亲教育程度低、厕所不可用、城市居住和母亲不洗手与儿童腹泻显著相关。