布鲁氏菌病中的双侧浆液性脉络膜脱离及其管理与结局：文献综述和病例报告

Bilateral serous choroidal detachment in brucellosis and its management and outcome: Literature review and case report.

作者信息

Adusumilli Himabindu, Krupa Lakshmi, Shetty Nitin S, Rao Sanjiv

机构信息

Vitreo Retinal Services, Manipal Hospitals, Bengaluru; Sri Kiran Institute of Ophthalmology, Kakinada, Godavari, Andhra Pradesh, India.

Vitreo Retinal Services, Manipal Hospitals, Bengaluru, Karnataka, India.

出版信息

Indian J Ophthalmol. 2020 Jun;68(6):1204-1206. doi: 10.4103/ijo.IJO_1418_19.

DOI:10.4103/ijo.IJO_1418_19

PMID:32461483

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7508090/

Abstract

To report an unusual case of a 71-year-old livestock farmer with systemic brucellosis and ocular involvement. Examination showed vitreous haze with bilateral serous choroidal detachment. He was treated with topical antibiotics and corticosteroids, Tab rifampicin 600 mg and doxycycline 100 mg for 6 weeks with visual recovery and complete resolution of serous choroidal detachment in 2 weeks. This is the first case of bilateral serous choroidal detachment in a case of systemic brucellosis. Immune-mediated complex and direct microbial invasion of uveal tissue leading to serous choroidal detachment is the proposed pathogenesis that responds well to topical corticosteroids.

摘要

报告一例71岁的家畜养殖户患系统性布鲁氏菌病并累及眼部的罕见病例。检查发现玻璃体混浊伴双侧浆液性脉络膜脱离。给予局部抗生素和皮质类固醇治疗，口服利福平600毫克和强力霉素100毫克，持续6周，视力恢复，浆液性脉络膜脱离在2周内完全消退。这是系统性布鲁氏菌病病例中双侧浆液性脉络膜脱离的首例。免疫介导的复合物和微生物直接侵袭葡萄膜组织导致浆液性脉络膜脱离是推测的发病机制，对局部皮质类固醇治疗反应良好。