Department of Ophthalmology, University Hospitals Leuven.
Laboratory of Ophthalmology, Department of Ophthalmology Neurosciences, KU Leuven, Leuven, Belgium.
J Glaucoma. 2020 Oct;29(10):995-998. doi: 10.1097/IJG.0000000000001606.
This study aimed to describe the clinical findings and management of eyes affected by uveal effusion syndrome.
We retrospectively evaluated the charts of 13 eyes of 8 consecutive patients diagnosed with uveal effusion syndrome attending the Ophthalmology Unit of the University Hospitals Leuven, Belgium, between 2007 and 2018. The presenting features, investigations, management, and outcomes were analyzed for each case.
Cataract surgery was the predisposing factor for uveal effusion in 6 eyes, 2 bilateral uveal effusions (4 eyes) were considered to be medication-induced, and in 3 eyes, the uveal effusion was described as idiopathic. Fundus examination of 5 of 13 eyes showed bullous choroidal detachment, treated with pars plana vitrectomy with superotemporal sclerectomy or transscleral punction. Fundoscopy showed uveal effusion without serous retinal detachment in 3 eyes. Serous retinal detachment accompanied by uveal swelling was observed in 3 eyes and the 2 remaining eyes presented with uveal swelling only. The 8 nonbullous choroidal detachments were treated in a conservative way. A rapid resolution of subretinal fluid and uveal effusion was observed in all cases.
A conservative approach with acetazolamide treatment or just observation was used in our case series in choroidal detachment without substantial visual loss if, over time, slow improvement was documented. However, further studies are needed to verify the effectiveness of the reported therapy.
本研究旨在描述葡萄膜渗出综合征患者眼部的临床表现和治疗方法。
我们回顾性评估了 2007 年至 2018 年间在比利时鲁汶大学医院眼科就诊的 8 例连续患者的 13 只眼的病历。分析了每个病例的表现特征、检查、治疗和结局。
6 只眼的葡萄膜渗出是白内障手术的诱发因素,2 例双眼葡萄膜渗出(4 只眼)被认为是药物引起的,3 只眼的葡萄膜渗出被描述为特发性。13 只眼中的 5 只眼底检查显示泡状脉络膜脱离,行玻璃体切除联合上方巩膜外冷凝术或经巩膜穿刺抽吸术治疗。3 只眼的眼底检查显示葡萄膜渗出而无浆液性视网膜脱离,3 只眼观察到浆液性视网膜脱离伴葡萄膜肿胀,2 只眼仅表现为葡萄膜肿胀。8 例非泡状脉络膜脱离采用保守治疗。所有病例均观察到视网膜下液和葡萄膜渗出迅速消退。
如果在随访过程中发现葡萄膜肿胀缓慢改善,且视力无明显下降,我们的病例系列中对无明显视功能损失的脉络膜脱离患者采用保守治疗(乙酰唑胺治疗或单纯观察)。然而,需要进一步的研究来验证所报道治疗方法的有效性。