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撒哈拉以南非洲男男性行为者中暴露后预防用药的障碍:一项在线横断面调查。

Barriers to post exposure prophylaxis use among men who have sex with men in sub-Saharan Africa: An online cross-sectional survey.

作者信息

Isano Sandra, Wong Rex, Logan Jenae, El-Halabi Soha, El-Khatib Ziad

机构信息

University of Global Health Equity (UGHE), Rwanda.

Yale University, USA.

出版信息

Prev Med Rep. 2020 Apr 28;19:101100. doi: 10.1016/j.pmedr.2020.101100. eCollection 2020 Sep.

Abstract

BACKGROUND

Curbing new HIV infections among MSM in SSA remains problematic, due to cultural beliefs, norms that oppose same-sex acts, and criminalization of same-sex acts. No study focused on barriers to PEP use in SSA region has been conducted. Our study focused on identifying barriers to Post-Exposure Prophylaxis (PEP) use among MSM in sub-Saharan Africa (SSA).

METHODS

An online cross-sectional survey was sent out to members of 14 Lesbian, Gay, Transgender, Bisexual, Queer (LGBTQ) associations in SSA, to identify barriers to PEP utilization in MSM. A total of 207 MSM from 22 countries in SSA completed the survey between 8 January 2019 and 23 February 2019. Descriptive statistics were generated, chi-square and backward stepwise logistic regression analysis were performed to evaluate the association between the outcome "PEP use" and other variables.

RESULTS

Most of the MSM were aged 18 to 30, and the majority (220, 74.6%) described themselves as gay. Rwanda had the highest number of respondents (117, 39.7% of the total), followed by Nigeria, Ghana and South-Africa.The majority of respondents reported having heard about PEP (234, 80.7%), and the average PEP correct knowledge level was 59%.Five characteristics were associated with increased odds of using PEP: Age, having vocational education, having heard of PEP, knowledge of where to get PEP, and having been refused housing.

CONCLUSION

There is a need for a collaborative effort between policy makers, key players in HIV prevention, and MSM associations in SSA to remove barriers to PEP uptake to promote optimal PEP utilization amongst MSM.

摘要

背景

由于文化信仰、反对同性行为的规范以及同性行为被定罪,在撒哈拉以南非洲地区(SSA)遏制男男性行为者(MSM)中的新增艾滋病毒感染仍然存在问题。目前尚未有针对SSA地区暴露后预防(PEP)使用障碍的研究。我们的研究聚焦于确定撒哈拉以南非洲地区男男性行为者使用暴露后预防措施(PEP)的障碍。

方法

向SSA地区14个女同性恋、男同性恋、跨性别者、双性恋、酷儿(LGBTQ)协会的成员发送了一项在线横断面调查,以确定男男性行为者使用PEP的障碍。2019年1月8日至2019年2月23日期间,来自SSA地区22个国家的207名男男性行为者完成了该调查。生成描述性统计数据,进行卡方检验和向后逐步逻辑回归分析,以评估“使用PEP”这一结果与其他变量之间的关联。

结果

大多数男男性行为者年龄在18至30岁之间,大多数(220人,占74.6%)称自己为同性恋。卢旺达的受访者数量最多(117人,占总数的39.7%),其次是尼日利亚、加纳和南非。大多数受访者表示听说过PEP(234人,占80.7%),PEP正确知识的平均水平为59%。有五个特征与使用PEP的几率增加相关:年龄、接受过职业教育、听说过PEP、知道在哪里可以获得PEP以及曾被拒绝提供住房。

结论

SSA地区的政策制定者、艾滋病毒预防的关键参与者和男男性行为者协会需要共同努力,消除PEP使用的障碍,以促进男男性行为者中PEP的最佳使用。

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