鼻腔软骨间叶性错构瘤。
Nasal Chondromesenchymal Hamartoma.
机构信息
Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Department of Otolaryngorhinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
出版信息
Head Neck Pathol. 2020 Dec;14(4):1041-1045. doi: 10.1007/s12105-020-01179-3. Epub 2020 May 27.
Abstract
Nasal chondromesenchymal hamartoma (NCMH) is a rare, benign lesion of the sinonasal tract. It usually presents as a polypoid mass in infants and older children. Imaging studies and endoscopy are required to delineate the extent of the lesion and aid in its excision. This unusual lesion is composed of proliferating mesenchymal and cartilaginous elements. Recently, a genetic association between NCMH and DICER1 mutation has been established. It is important for pathologists to be familiar with this entity to avoid misdiagnosis since the lesion is benign and surgical excision is curative.
摘要
鼻腔软骨间叶性错构瘤（Nasal Chondromesenchymal Hamartoma，NCMH）是一种罕见的、良性的鼻窦内病变。它通常表现为婴儿和大龄儿童的息肉样肿块。影像学研究和内镜检查是必要的，以描绘病变的范围，并帮助切除。这个不常见的病变由增生的间叶和软骨成分组成。最近，NCMH 与 DICER1 突变之间的遗传关联已被确定。病理学家熟悉这个实体非常重要，以避免误诊，因为病变是良性的，手术切除是可以治愈的。
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