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[血管平滑肌细胞阈下刺激的功能效应]

[Functional effects of subthreshold stimulation of smooth muscle cells of the blood vessel].

作者信息

Govyrin V A, Malovichko N A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1988 Nov;74(11):1622-7.

PMID:3246282
Abstract

The effect of subthreshold electrical stimulation of smooth muscle cells of the vessel wall upon the level of tonic tension developed by the smooth muscle in response to distention, was studied in isolated segments of the rat tail artery. Low concentrations of catecholamines--30-300 times lesser than those ordinarily observed in the blood--as well as subthreshold electrical stimuli were shown to affect functional properties of the blood vessel's smooth muscles, potentiating the tonic tension developed by the vessel in response to distention. Calcium ions are necessary for the development of potentiating effect of the subthreshold stimuli upon the tone of the blood vessels.

摘要

在大鼠尾动脉离体节段中,研究了血管壁平滑肌细胞的阈下电刺激对平滑肌因扩张而产生的紧张性张力水平的影响。低浓度的儿茶酚胺(比通常在血液中观察到的浓度低30 - 300倍)以及阈下电刺激均被证明会影响血管平滑肌的功能特性,增强血管因扩张而产生的紧张性张力。钙离子是阈下刺激对血管张力产生增强作用所必需的。

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