Ophthalmology Department, Retina Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ophthalmology Department, Ocular Immunology and Uveitis Foundation, Waltham, Massachusetts, USA.
Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1363-1365. doi: 10.1080/09273948.2020.1754433. Epub 2020 May 28.
: Here, we report a case of otherwise typical Fuchs uveitis (FU) who presented with atypical keratic precipitates (KPs).: A 38 year-old man presented with decreased vision in the right eye. Best corrected visual acuity was 2/10 in the right eye and 10/10 in the left eye. He was known to have advanced glaucoma in the right eye. The presence of KPs, iris smoothness, posterior subcapsular cataract, vitreous cells, as well as imaging characteristics were in complete agreement with the classical picture of FU in this eye. However, KPs varied in size from small to large and had a triangular distribution over the inferior corneal endothelium. A tendency to confluence and pigments were also observed in some KPs. This is in sharp contrast with the description of typical diffuse, small, white, stellate KPs, which has been emphasized as a defining feature of FU in recent publications. To rule out other uveitis entities, a comprehensive laboratory workup was done, as well as a molecular assay on aqueous for common infectious uveitides with the similar clinical picture.: Ophthalmologists should be aware that FU can manifest with atypical KPs in a minority of patients to prevent erroneous diagnosis and unnecessary treatments.
: 在这里,我们报告了一例典型的 Fuchs 葡萄膜炎(FU)患者,其出现了非典型的角膜后沉着物(KPs)。: 一名 38 岁男性因右眼视力下降就诊。右眼最佳矫正视力为 2/10,左眼为 10/10。他被诊断为右眼晚期青光眼。该眼的 KPs、虹膜光滑度、后囊下白内障、玻璃体细胞以及影像学特征均与 FU 的典型表现完全一致。然而,KPs 的大小从小到大不等,在下角膜内皮呈三角形分布。一些 KPs 也观察到有融合和色素的趋势。这与最近出版物中强调的典型弥漫性、小、白色、星状 KPs 的描述形成鲜明对比,后者被认为是 FU 的一个明确特征。为排除其他葡萄膜炎,我们进行了全面的实验室检查,以及针对具有相似临床表现的常见感染性葡萄膜炎的房水分子检测。: 眼科医生应该意识到,FU 在少数患者中可能表现为非典型 KPs,以防止误诊和不必要的治疗。