Department of Medicine, University of British Columbia, BC V5Z 4R4, Vancouver, Canada.
Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, 00014 Finland.
Pathog Dis. 2020 Jul 1;78(5). doi: 10.1093/femspd/ftaa022.
Gynecological and obstetrical infectious diseases are an important component of women's health. A system approach to gynecological and obstetrical infection helps unify and classify microbial etiology and pathogenesis within a clinical anatomical framework of lower and upper genital tract syndromes. The reproductive system of women includes the vulva, vagina, cervix, uterus, fallopian tubes and ovaries. During pregnancy, additional tissues include the chorioamnion and placenta together with the fetus and amniotic fluid. We review in two parts reproductive system infection syndromes in women using selected research results to illustrate the clinical utility of the system approach in terms of diagnosis, treatment and prevention. We conclude that a reproductive system perspective will lead to improvements in understanding, management and prevention of these diseases.
妇科和产科感染性疾病是妇女健康的重要组成部分。采用系统方法研究妇科和产科感染有助于将微生物病因学和发病机制统一并分类，纳入下生殖道和上生殖道综合征的临床解剖学框架内。女性生殖系统包括外阴、阴道、宫颈、子宫、输卵管和卵巢。在妊娠期间，还包括绒毛膜-羊膜和胎盘以及胎儿和羊水。我们分两部分综述女性生殖系统感染综合征，选用部分研究结果说明系统方法在诊断、治疗和预防方面的临床应用。我们的结论是，从生殖系统角度出发，将有助于加深对这些疾病的认识，改善其管理和预防。
