Faleye T O C, Ifeorah M I, Olayinka O A, Oluremi B, George U E, Arowolo O A, Omoruyi E C, Donbraye E, Oyero A O, Adewumi O M, Adeniji J A
Center for Human Virology and Genomics, Department of Microbiology, Nigerian Institute of Medical Research, Lagos, Nigeria.
Department of Virology, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Microbiol Resour Announc. 2020 May 28;9(22):e00094-20. doi: 10.1128/MRA.00094-20.
Here, we describe the near-complete genome of an enterovirus F (EV-F) isolate from Nigeria. The obtained sequence was 7,378 nucleotides (nt) long and encodes 2 open reading frames (ORFs), an upstream ORF (uORF; 56 amino acids [aa]) and a polyprotein ORF (ppORF; 2,167 aa). Both ORFs overlap but are in different reading frames, with the uORF in a +1 reading frame relative to the ppORF.
在此,我们描述了一株来自尼日利亚的肠道病毒F(EV-F)分离株的近乎完整的基因组。获得的序列长度为7378个核苷酸(nt),编码2个开放阅读框(ORF),一个上游开放阅读框(uORF;56个氨基酸 [aa])和一个多聚蛋白开放阅读框(ppORF;2167个aa)。两个开放阅读框相互重叠,但处于不同的阅读框,uORF相对于ppORF处于+1阅读框。