College of Veterinary Medicine, Key Laboratory for Zoonoses Research, Ministry of Education, Jilin University, 5333 Xian Road, Changchun, 130062, Jilin, China.
Key Laboratory for Zoonoses Research, Ministry of Education, Changchun, Jilin, China.
Arch Virol. 2019 Oct;164(10):2551-2558. doi: 10.1007/s00705-019-04331-9. Epub 2019 Jul 18.
Here, we report two novel enteroviruses, designated as SD-S67 and SD-S68, isolated from a goat farm. Their complete genome sequences were determined and found to be 7455 and 7465 nucleotides in length, respectively. Molecular characterization revealed that SD-S67 is closely related to bovine enterovirus strain 261 and that SD-S68 to caprine enterovirus strain CEV-JL14. Phylogenetic analysis showed that SD-S67 clustered with members of the species Enterovirus F, and that SD-S68 clustered with enteroviruses of goats and sheep. Recombination analysis showed that SD-S67 is likely to have undergone several recombination events in the process of its evolution. To the best of our knowledge, this is the first report of an enterovirus F isolate from a goat and of a coinfection with enteroviruses of different species in the same goat herd.
这里，我们报告了两种新型肠病毒，分别命名为 SD-S67 和 SD-S68，从一个山羊养殖场分离得到。我们测定了它们的完整基因组序列，分别长 7455 和 7465 个核苷酸。分子特征表明，SD-S67 与牛肠病毒 261 株密切相关，而 SD-S68 与山羊肠病毒 JL14 株密切相关。系统进化分析表明，SD-S67 聚类于肠道病毒 F 种成员中，而 SD-S68 聚类于山羊和绵羊肠病毒中。重组分析表明，SD-S67 在进化过程中可能发生了多次重组事件。据我们所知，这是首次从山羊中分离到肠道病毒 F 株，也是在同一个山羊群中同时感染不同种肠病毒的首例报告。
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