人扁桃体细胞在体外形成抗体。
Antibody formation by human tonsil cells in vitro.
作者信息
Baumöhl Z, Kellerhals B, Stolp W, Lefkovits I
出版信息
Clin Exp Immunol. 1977 Apr;28(1):116-22.
The ability of human tonsil lymphocytes to give an anti-SRBC response in conventional cultures and in microcultures was studied. It was found that about two-thirds of tonsils responded with a significant number of plaque-forming cells (PFC), and that in some instances the response could be augmented if allogeneic tonsil cell (irradiated or intact) were added. Moreover, tonsil lymphocytes which failed to give a response on their own often responded upon addition of an appropriate number of allogeneic tonsil cells. The response was remarkably improved if allogeneic tonsil supernatant or conditioned medium were added. An anti-SRBC response was also obtained if SRBC was omitted from the cultures. The frequency of anti-SRBC specific B cells was estimated as 1/60000 (f = 1-7 X 10(-5)).
研究了人扁桃体淋巴细胞在常规培养和微量培养中产生抗绵羊红细胞（SRBC）反应的能力。发现约三分之二的扁桃体产生了大量的噬斑形成细胞（PFC），并且在某些情况下，如果加入同种异体扁桃体细胞（经照射或完整的），反应会增强。此外，自身无反应的扁桃体淋巴细胞在加入适当数量的同种异体扁桃体细胞后常常会产生反应。如果加入同种异体扁桃体上清液或条件培养基，反应会显著改善。如果培养物中省略SRBC，也能获得抗SRBC反应。抗SRBC特异性B细胞的频率估计为1/60000（f = 1 - 7×10⁻⁵）。
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