Day Andrew S, Lemberg Daniel A
Department of Paediatrics, University of Otago Christchurch, Christchurch, New Zealand.
Department of Gastroenterology, Sydney Children's Hospital, Sydney, New South Wales, Australia.
J Paediatr Child Health. 2020 Nov;56(11):1731-1734. doi: 10.1111/jpc.14925. Epub 2020 May 29.
Crohn disease and ulcerative colitis are the two main types of inflammatory bowel disease. High rates of these conditions are seen in Australasian children - furthermore, increasing rates have been evident in recent years. Children can present with typical symptoms of abdominal pain, diarrhoea, haematochezia and/or weight loss. Atypical presentations (such as skin lesions or isolated short stature) can also occur: these may be associated with delays in the consideration and diagnosis of IBD. Initial steps in establishing a diagnosis of IBD include delineation of inflammatory markers exclusion of any other likely aetiology. Definitive diagnosis relies upon key endoscopic, histologic and radiological findings. Overall management of IBD encompasses care within a team-based, child and family-focused, multi-disciplinary setting.
克罗恩病和溃疡性结肠炎是炎症性肠病的两种主要类型。在澳大拉西亚儿童中,这些疾病的发病率很高——此外,近年来发病率一直在上升。儿童可能出现腹痛、腹泻、便血和/或体重减轻等典型症状。也可能出现非典型表现(如皮肤病变或孤立性身材矮小):这些可能与炎症性肠病的诊断延迟有关。建立炎症性肠病诊断的初始步骤包括确定炎症标志物,排除任何其他可能的病因。明确诊断依赖于关键的内镜、组织学和放射学检查结果。炎症性肠病的整体管理包括在以团队为基础、以儿童和家庭为中心的多学科环境中进行护理。