Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Department of Thoracic Oncology, Hyogo College of Medicine, Nishinomiya, Japan.
Cancer Invest. 2020 Jul;38(6):356-364. doi: 10.1080/07357907.2020.1776313. Epub 2020 Jun 16.
Pleural effusion adenosine deaminase (ADA) levels are elevated in various diseases. We investigated whether pleural effusion ADA levels differ among patients with malignant pleural mesothelioma (MPM), lung cancer (LC), and benign diseases, including tuberculous pleurisy. We examined 329 patients from February 2002 to July 2013. There were 131 MPM cases with ADA levels of 32.29 IU/L; 117 LC cases with ADA levels of 21.12 IU/L; 54 benign disease cases with ADA levels of 20.98 IU/L. A significant difference existed in pleural effusion ADA levels between MPM and benign disease patients. Pleural effusion ADA levels were significantly higher in MPM patients.
胸腔积液腺苷脱氨酶（ADA）水平在各种疾病中升高。我们研究了恶性胸膜间皮瘤（MPM）、肺癌（LC）和良性疾病（包括结核性胸膜炎）患者胸腔积液 ADA 水平是否存在差异。我们检查了 2002 年 2 月至 2013 年 7 月的 329 名患者。131 例 MPM 患者 ADA 水平为 32.29IU/L；117 例 LC 患者 ADA 水平为 21.12IU/L；54 例良性疾病患者 ADA 水平为 20.98IU/L。MPM 和良性疾病患者胸腔积液 ADA 水平存在显著差异。MPM 患者胸腔积液 ADA 水平显著升高。
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