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核医学:放射性同位素技术在心血管疾病诊断中的应用概述。

Nuclear cardiology: an overview of radioisotope techniques used in the diagnostic workup of cardiovascular disorders.

机构信息

Nuclear Medicine Department, Greater Poland Cancer Centre, Poznań, Poland

1st Department of Cardiology, University of Medical Sciences, Poznań, Poland.

出版信息

Kardiol Pol. 2020 Jun 25;78(6):520-528. doi: 10.33963/KP.15396. Epub 2020 May 28.

DOI:10.33963/KP.15396
PMID:32469191
Abstract

Cardiovascular diseases are the most common cause of death in patients over 60 years old. Pivotal imaging modalities in cardiac diagnostic workup are echocardiography, magnetic resonance, multi‑row detector computed tomography, coronary angiography, and radioisotope tests. In this study, we summarize the techniques of nuclear medicine (positron emission tomography, single‑photon emission computed tomography, radionuclide ventriculography) that could be implemented in the cardiovascular diagnostic algorithms. Despite being acknowledged in a few cardiology guidelines, these imaging methods are still underestimated by practitioners. Nevertheless, noninvasive diagnostic tools are of increasing potential and should be implemented whenever possible. We discuss the usefulness of particular techniques in the management of patients with obstructive and nonobstructive coronary artery disease, including assessment of myocardial perfusion, contractility, viability, and detection of unstable atherosclerotic plaques. Radioisotope imaging can also be valuable in the diagnostic workup of infective endocarditis, as well as cardiac sarcoidosis and amyloidosis. Apart from theoretical principles of nuclear cardiology, we also provide 3 case reports illustrating a practical implementation of these imaging modalities.

摘要

心血管疾病是 60 岁以上患者死亡的最常见原因。心脏诊断工作中的关键成像方式包括超声心动图、磁共振成像、多排探测器计算机断层扫描、冠状动脉造影和放射性同位素检查。在本研究中,我们总结了核医学(正电子发射断层扫描、单光子发射计算机断层扫描、放射性核素心室造影)技术,这些技术可应用于心血管诊断算法中。尽管在一些心脏病学指南中得到认可,但这些影像学方法仍被临床医生低估。然而,无创诊断工具的潜力越来越大,应尽可能地加以应用。我们讨论了特定技术在评估阻塞性和非阻塞性冠状动脉疾病患者中的用途,包括心肌灌注、收缩力、活力以及不稳定粥样斑块的检测。放射性同位素成像在感染性心内膜炎、心脏结节病和淀粉样变性的诊断工作中也具有重要价值。除了核心脏病学的理论原理外,我们还提供了 3 个病例报告,说明了这些影像学方法的实际应用。

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