Post-Graduate Program in Dentistry, University Federal de Minas Gerais, Belo Horizonte, Brazil.
Faculty President Antônio Carlos, Teófilo Otoni, Brazil.
Oral Dis. 2021 Sep;27(6):1346-1355. doi: 10.1111/odi.13439. Epub 2020 Jun 25.
The aim of this systematic review and meta-analysis was to evaluate the experience of dental caries in individuals pre- or postliver transplant.
Searches in PubMed, Scopus, Web of Science, Ovid, and Lilacs from databases' inception date up to April 2020 were undertaken. Gray literature and manual searches were also conducted. Observational studies were eligible. The retrieved references were evaluated by two independent reviewers. Meta-analysis and risk of bias assessment using the University of Adelaide tool were conducted. The strength of the evidence was assessed with GRADE.
The search retrieved 1990 references. Twenty-four cross-sectional studies were included. One subgroup analysis demonstrated no significant difference in the number of teeth with dental caries between pre-liver transplant and healthy individuals (mean difference = 1.65, confidence interval = -0.87 to 4.17). The prevalence of dental caries among pre-liver transplant individuals was 73.82% and in the post-transplant individuals was 72.83%. In the included studies, the main concern regarding risk of bias was the absence of control for confounding variables. The strength of the evidence was very low.
Dental caries may be a relevant issue in pre- and postliver transplant individuals. Oral health counseling should be included in the care of pre- and/or postliver transplant individuals.
本系统评价和荟萃分析的目的是评估肝移植前后个体的龋齿经历。
从数据库建立日期到 2020 年 4 月，在 PubMed、Scopus、Web of Science、Ovid 和 Lilacs 中进行了检索。还进行了灰色文献和手动搜索。合格的研究为观察性研究。检索到的参考文献由两位独立的评审员进行评估。使用阿德莱德大学工具进行荟萃分析和偏倚风险评估。使用 GRADE 评估证据的强度。
搜索共检索到 1990 篇参考文献。纳入了 24 项横断面研究。一项亚组分析表明，肝移植前和健康个体的龋齿牙齿数量无显著差异（平均差异=1.65，置信区间=-0.87 至 4.17）。肝移植前个体的龋齿患病率为 73.82%，移植后个体的龋齿患病率为 72.83%。在纳入的研究中，主要关注的偏倚风险是缺乏混杂变量的控制。证据的强度非常低。
龋齿可能是肝移植前后个体的一个重要问题。应在肝移植前后个体的护理中纳入口腔健康咨询。
