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自闭症谱系障碍中的胃肠道、营养、内分泌和微生物组状况。

Gastrointestinal, nutritional, endocrine, and microbiota conditions in autism spectrum disorder.

机构信息

Hospital de Clínicas José de San Martín (HCJSM), Buenos Aires, R. Argentina.

Equipo Trastorno del Espectro Autista-Enfoque Integrador (TEA-EI).

出版信息

Arch Argent Pediatr. 2020 Jun;118(3):e271-e277. doi: 10.5546/aap.2020.eng.e271.

DOI:10.5546/aap.2020.eng.e271
PMID:32470264
Abstract

Gastrointestinal, nutritional, metabolic, endocrine, and microbiota medical problems in pediatric patients diagnosed with autism spectrum disorder (ASD) are some of the coexisting medical conditions in ASD diagnosis. Their prevalence reaches more than 91 % for gastrointestinal problems, up to 89 % for nutritional and metabolic disorders, more than 50 % for thyroid dysfunction, and up to 100 % for microbiota-related conditions. There is an urgency for medical practice to be updated and to include the assessment, testing, diagnosis, and treatment of these coexisting medical conditions in ASD diagnosis in the pediatric, adolescent, and adult population. A strict management of such conditions results in positive changes in the quality of life and symptoms based on which ASD is diagnosed many times. It should be based on high-quality scientific evidence with an adequate medical care and control.

摘要

在被诊断为自闭症谱系障碍(ASD)的儿科患者中,胃肠道、营养、代谢、内分泌和微生物群医学问题是 ASD 诊断中的一些共存医疗条件。胃肠道问题的患病率超过 91%,营养和代谢紊乱的患病率高达 89%,甲状腺功能障碍的患病率超过 50%,与微生物群相关的疾病的患病率高达 100%。医疗实践需要更新,包括在儿科、青少年和成年人群中对 ASD 诊断中的这些共存医疗条件进行评估、测试、诊断和治疗。严格管理这些疾病可以根据诊断 ASD 的许多症状,改善生活质量。它应该基于高质量的科学证据,并进行适当的医疗保健和控制。

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