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双相障碍患者共病强迫症对自杀的影响。

Impact of comorbid obsessive-compulsive disorder on suicidality in patients with bipolar disorder.

机构信息

Department of Neuroscience "Rita Levi Montalcini", University of Turin, Via Cherasco 15, 10126, Turin, Italy.

Mental Health Department of Alba and Bra, ASL CN2, Via Monte di Pietà 21, 12042 Bra (CN), Italy.

出版信息

Psychiatry Res. 2020 Aug;290:113088. doi: 10.1016/j.psychres.2020.113088. Epub 2020 May 21.

Abstract

This study evaluated the impact of comorbid OCD on suicide attempt risk and suicide methods in 990 patients with main diagnosis of BD. Two hundred and one patients (20.3%) had lifetime comorbid OCD. No significant differences were found comparing rates of lifetime suicide attempts between patients with or without comorbid OCD (30.3% vs 24.6%). In the subgroup of patients with concomitant OCD more subjects performed suicide attempts with violent methods (48.3% vs 28.7%). Therefore, our results suggest a correlation between comorbid OCD and violent suicide attempts. This finding is worthy of interest and deserves to be explored by further studies.

摘要

这项研究评估了共病强迫症(OCD)对 990 名主要诊断为双相情感障碍(BD)患者自杀企图风险和自杀方法的影响。201 名患者(20.3%)有共病 OCD 的病史。比较有无共病 OCD 的患者一生中自杀企图的发生率,并未发现显著差异(30.3%比 24.6%)。在合并 OCD 的患者亚组中,更多的患者使用暴力手段自杀(48.3%比 28.7%)。因此,我们的结果表明共病 OCD 与暴力自杀企图之间存在相关性。这一发现值得关注,需要进一步的研究来探讨。

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