Fairchild Berry, Wei Shuyan, Bartz-Kurycki Marisa, Rose Jessica F, Greives Matthew R
From the Division of Plastic Surgery, Department of Surgery, McGovern Medical School at the University of Texas Health Sciences Center at Houston.
Center for Translational Injury Research, Division of Pediatric Surgery, Department of Pediatric Surgery.
Ann Plast Surg. 2020 Dec;85(6):608-611. doi: 10.1097/SAP.0000000000002311.
Symptomatic macromastia causes negative physical and psychosocial effects, which support the need for early intervention, even in the adolescent population (Plast Reconstr Surg 2012;130:785-789). Reduction mammaplasty is a proven treatment that reliably addresses symptoms from macromastia. The National Surgical Quality Improvement Program-Pediatric is the leading nationally validated, risk-adjusted, outcomes-based program to measure and improve the quality of surgical care (Pediatrics 2012;130:e339-e346). In adults, obesity is associated with increased early postoperative complications after mammaplasty (Pediatrics 2017;140(5)). We hypothesized that obesity would increase the incidence of postoperative complications in pediatric patients undergoing reduction mammaplasty.
The National Surgical Quality Improvement Program-Pediatric database was queried for female patients 18 years or younger who underwent reduction mammaplasty from January 2012 to December 2017 using Current Procedural Terminology code 19318. Demographic, clinical, and outcomes data were abstracted from the database. A composite postoperative adverse events variable was created from a list of 21 individual adverse events. Patients were stratified by presence of obesity (body mass index ≥30 kg/m) on univariate analyses. Multivariable logistic regression was used to determine factors associated with any postoperative adverse events.
A total of 542 female patients underwent reduction mammaplasty, with 48% of the cohort being obese. Patients were similar in age (median, 17 years) and comorbidities between obese and nonobese groups. Obese patients were more likely to be African American, have higher American Society of Anesthesiologists class, and endure longer operations. Composite adverse event rates were significantly higher in the obese group (7% vs 2%, P = 0.013). Individual adverse events were similar between groups, with the exception of 30-day readmissions, which was higher in the obese group (3% vs 1%, P = 0.04). On multivariable logistic regression, obesity increased the odds of having a postoperative adverse event by 3-fold after adjusting for operative duration.
Obesity was significantly associated with greater postoperative adverse events in obese adolescent females after reduction mammaplasty compared with their nonobese counterparts. Although recorded rates of adverse events after reduction mammaplasty were low, preoperative weight loss programs may further improve outcomes for obese pediatric populations undergoing reduction mammaplasty.
有症状的巨乳症会对身体和心理产生负面影响,这支持了即使在青少年人群中也需要早期干预的观点(《整形再造外科》2012年;130:785 - 789)。乳房缩小术是一种经证实的治疗方法,能有效解决巨乳症的症状。国家外科质量改进计划 - 儿科项目是全国领先的经过验证、基于风险调整且以结果为基础的项目,用于衡量和提高外科护理质量(《儿科学》2012年;130:e339 - e346)。在成年人中,肥胖与乳房缩小术后早期并发症增加有关(《儿科学》2017年;140(5))。我们假设肥胖会增加接受乳房缩小术的儿科患者术后并发症的发生率。
利用当前手术操作术语代码19318,查询国家外科质量改进计划 - 儿科数据库中2012年1月至2017年12月期间接受乳房缩小术的18岁及以下女性患者。从数据库中提取人口统计学、临床和结果数据。从21项个体不良事件列表中创建一个综合术后不良事件变量。在单因素分析中,根据是否存在肥胖(体重指数≥30 kg/m²)对患者进行分层。使用多变量逻辑回归来确定与任何术后不良事件相关的因素。
共有542名女性患者接受了乳房缩小术,其中48%的队列患者肥胖。肥胖组和非肥胖组患者在年龄(中位数为17岁)和合并症方面相似。肥胖患者更可能是非裔美国人,美国麻醉医师协会分级更高,且手术时间更长。肥胖组的综合不良事件发生率显著更高(7%对2%,P = 0.013)。除30天再入院率外,两组间个体不良事件相似,肥胖组的30天再入院率更高(3%对1%,P = 0.04)。在多变量逻辑回归分析中,在调整手术持续时间后,肥胖使术后出现不良事件的几率增加了3倍。
与非肥胖的青少年女性相比,肥胖的青少年女性在乳房缩小术后出现的术后不良事件明显更多。尽管乳房缩小术后记录的不良事件发生率较低,但术前减肥计划可能会进一步改善接受乳房缩小术的肥胖儿科人群的治疗效果。