高频听力损失在正常听力个体中的早期检测。

Early Detection of High-frequency Presbycusis Among Normal Hearing Individuals.

机构信息

Department of Otorhinolaryngology, School of Medical Sciences.

School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

出版信息

Otol Neurotol. 2020 Sep;41(8):e989-e992. doi: 10.1097/MAO.0000000000002725.

DOI:10.1097/MAO.0000000000002725

PMID:32472918

Abstract

BACKGROUND

Presbycusis is an age-related sensorineural hearing loss and it may reduce quality of life. We conducted a study to establish the prevalence of high-frequency presbycusis in normal hearing individuals and to validate the role of extended high-frequency distortion product otoacoustic emission (DPOAE) in the screening.

METHOD

A cross-sectional study was conducted among 205 normal hearing adult participants with an age range between 25 and 54 years old. Hearing analysis with extended high-frequency pure-tone audiometry (PTA) and high-frequency DPOAE was carried out for all eligible participants. High-frequency presbycusis was considered to be present when the impairment of more than 25 dB occurs at higher than 8 kHz frequencies on both ears.

RESULTS

Prevalence of high-frequency presbycusis using extended PTA was 31.7 (95% CI: 25.3, 38.1) and using high-frequency DPOAE was 57.4 (95% CI: 50.7, 64.4). The sensitivity and specificity of high-frequency DPOAE in detecting high-frequency presbycusis were 72.3 and 49.3% respectively with positive predictive value of 39.8% and negative predictive value of 79.3%. The association between age and high-frequency presbycusis was significant based on high-frequency DPOAE (p = 0.029).

CONCLUSIONS

The prevalence of high-frequency hearing loss is higher with increasing in age. High-frequency DPOAE may be used as a screening tool followed by confirmation using extended PTA. The early detection of presbycusis is important so that measures can be taken to prevent more severe problems developing.

摘要

背景

老年性聋是一种与年龄相关的感音神经性听力损失，它可能降低生活质量。我们进行了一项研究，以确定正常听力个体中高频听力损失的患病率，并验证扩展高频畸变产物耳声发射（DPOAE）在筛查中的作用。

方法

对 205 名年龄在 25 至 54 岁之间的正常听力成年人进行横断面研究。对所有符合条件的参与者进行扩展高频纯音听阈测试（PTA）和高频 DPOAE 听力分析。当双耳高频频率超过 8 kHz 时，听力损失超过 25 dB 时，认为存在高频听力损失。

结果

使用扩展 PTA 检测高频听力损失的患病率为 31.7%（95%CI：25.3%，38.1%），使用高频 DPOAE 的患病率为 57.4%（95%CI：50.7%，64.4%）。高频 DPOAE 检测高频听力损失的敏感性和特异性分别为 72.3%和 49.3%，阳性预测值为 39.8%，阴性预测值为 79.3%。基于高频 DPOAE，年龄与高频听力损失之间存在显著相关性（p=0.029）。