Chida E, Satoh N, Kawanami M, Kashiwamura M, Sakamoto T, Fukuda S, Inuyama Y
Department of Otolaryngology, Hokkaido University School of Medicine, Sapporo.
Nihon Jibiinkoka Gakkai Kaiho. 1997 Apr;100(4):436-43. doi: 10.3950/jibiinkoka.100.436.
To establish clinical criteria for distortion product otoacoustic emissions (DPOAEs) in order to distinguish normal-hearing from hearing-impaired ears, DPOAEs were measured and evaluated in 325 normal and 291 cochlear-impaired human ears using an ILO92 Otoacoustic Emission Analyzer. The background noise level was too variational in each individual ear to ignore in DPOAE measurements. Therefore, the value of the difference between the DPOAE amplitude and the background noise level (DPOAE noise) was calculated and compared with the pure tone threshold at 1 kHz, 2 kHz and 4 kHz. It was difficult, however, to precisely separate normal-hearing and hearing impaired ears with DPOAE noise values because many normal ears presented small amplitudes of DPOAEs and some impaired ears showed high amplitudes. Therefore, cumulative distributions of sensitivity (normal hearing ears identified as normal hearing) and specificity (hearing impaired ears identified as hearing impaired) were constructed and used to calculate a cut off point for DPOAE-noise in order to separate normal hearing from hearing impaired ears. It is considered that the cut-off points (DPOAE noise values of 7.3 dB at 1 kHz, 10.3 dB at 2 kHz and 16.1 dB at 4 kHz) at which the false alarm rates (1 specificity: the rate of hearing impaired ears incorrectly identified as normal hearing) correspond to 5% can be useful for clinical evaluation of DPOAEs.
为了建立畸变产物耳声发射(DPOAE)的临床标准,以便区分正常听力和听力受损的耳朵,使用ILO92耳声发射分析仪对325只正常耳朵和291只耳蜗受损的人耳进行了DPOAE测量和评估。在DPOAE测量中,每只耳朵的背景噪声水平变化太大,不容忽视。因此,计算了DPOAE幅度与背景噪声水平之间的差值(DPOAE噪声),并将其与1kHz、2kHz和4kHz处的纯音阈值进行比较。然而,很难用DPOAE噪声值精确区分正常听力和听力受损的耳朵,因为许多正常耳朵的DPOAE幅度较小,而一些受损耳朵的幅度较高。因此,构建了敏感性(将正常听力耳朵识别为正常听力)和特异性(将听力受损耳朵识别为听力受损)的累积分布,并用于计算DPOAE噪声的截止点,以便区分正常听力和听力受损的耳朵。据认为,误报率(1-特异性:将听力受损耳朵错误识别为正常听力的比率)对应于5%时的截止点(1kHz时为7.3dB、2kHz时为10.3dB、4kHz时为16.1dB的DPOAE噪声值)可用于DPOAE的临床评估。