Suppr超能文献

血管内动脉瘤修复术后择期晚期开放转换与腹主动脉瘤一期开放修复的预后相当。

Elective late open conversion after endovascular aneurysm repair is associated with comparable outcomes to primary open repair of abdominal aortic aneurysms.

作者信息

Chastant Robin, Canaud Ludovic, Ozdemir Baris Ata, Aubas Pierre, Molinari Nicolas, Picard Eric, Branchereau Pascal, Marty-Ané Charles-Henri, Alric Pierre

机构信息

Department of Thoracic and Vascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

Department of Thoracic and Vascular Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.

出版信息

J Vasc Surg. 2021 Feb;73(2):502-509.e1. doi: 10.1016/j.jvs.2020.05.033. Epub 2020 May 27.

Abstract

OBJECTIVE

Three of four patients with infrarenal abdominal aortic aneurysm are now treated with endovascular aneurysm repair (EVAR). The incidence of secondary procedures and surgical conversions is increasing for a population theoretically unfit for open surgery. The indications and outcomes of late open surgical conversions after EVAR in a high-volume tertiary vascular unit are reported.

METHODS

This retrospective single-center study includes all patients who underwent a late open conversion between January 1996 and July 2018. Data were collected from records on patient demographics, operative indications, surgical strategy, perioperative outcomes, and medium-term survival.

RESULTS

Sixty-two consecutive patients (88.7% male) with a mean age of 77.5 years are included. The median duration since index EVAR was 38.5 months; 65% of stent grafts requiring late open conversion had suprarenal fixation. Indications included 22.6% type IA, 16.1% type IB, and 45.2% type II endoleaks; 12.9% graft thrombosis; and 14.5% endoprosthesis infection. Complete endograft explantation was performed in 37.1% of patients and a partial explantation in 54.8%, whereas 8.1% of stent grafts were wholly preserved in situ. Overall 30-day mortality was 12.9% (n = 8) in the cohort and 2.7% for elective patients. The all-cause morbidity rate was 40.1%, and the median length of hospital stay was 9 days. After follow-up of 28.4 months (range, 1.8-187.3 months), all-cause survival was 58.8%. Avoidance of aortic clamping (P = .006) and elective procedures (P = .019) were associated with a significant reduction in the length of hospital stay. Moreover, the 30-day mortality (P = .002), occurrence of postoperative renal dysfunction (P = .004), and intestinal ischemia (P = .017) were increased in the emergency setting. Excluding cases with rupture or infection, survival estimates were 97%, 97%, and 71% at 1 year, 2 years, and 5 years, respectively.

CONCLUSIONS

Technically more complex than primary open surgery, late open conversion is a procedure that generates an acceptable perioperative risk when it is performed in a high-volume aortic surgical center. Elective open conversion is associated with excellent early and late outcomes. Endograft preservation strategies decrease perioperative morbidity.

摘要

目的

肾下腹主动脉瘤患者中,现在有四分之三接受血管腔内动脉瘤修复术(EVAR)治疗。对于理论上不适合开放手术的人群,二次手术和手术转换的发生率正在上升。本文报告了在一个大型三级血管病治疗中心,EVAR术后晚期开放手术转换的适应症和结果。

方法

这项回顾性单中心研究纳入了1996年1月至2018年7月期间所有接受晚期开放转换手术的患者。从患者人口统计学、手术适应症、手术策略、围手术期结果和中期生存率的记录中收集数据。

结果

纳入62例连续患者(88.7%为男性),平均年龄77.5岁。自首次EVAR以来的中位时间为38.5个月;需要晚期开放转换的支架移植物中,65%有肾上固定。适应症包括22.6%的IA型、16.1%的IB型和45.2%的II型内漏;12.9%的移植物血栓形成;以及14.5%的人工血管感染。37.1%的患者进行了完全人工血管外植,54.8%进行了部分外植,而8.1%的支架移植物原位完全保留。该队列的总体30天死亡率为12.9%(n = 8),择期手术患者为2.7%。全因发病率为40.1%,中位住院时间为9天。随访28.4个月(范围1.8 - 187.3个月)后,全因生存率为58.8%。避免主动脉阻断(P = .006)和择期手术(P = .019)与住院时间显著缩短相关。此外,急诊情况下30天死亡率(P = .002)、术后肾功能不全发生率(P = .004)和肠缺血发生率(P = .017)均升高。排除破裂或感染病例后,1年、2年和5年的生存估计分别为97%、97%和71%。

结论

晚期开放转换在技术上比初次开放手术更复杂,但在大型主动脉外科中心进行时,是一种围手术期风险可接受的手术。择期开放转换与良好的早期和晚期结果相关。人工血管保留策略可降低围手术期发病率。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验